New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. 产品名称/活性 Date Added
8802 MPD 2 Dec 2024
SARS-CoV-2 Mpro Degrader (PROTAC®)
8817 CoraFluor™ 1, Haloalkane Dec 2024
Cell impermeable terbium cryptate FRET donor for TR-FRET assay development, with chloroalkane ligand
8818 CoraFluor™ 2, Haloalkane Dec 2024
Cell permeable terbium cryptate FRET donor for TR-FRET assay development, with chloroalkane ligand
8831 HB-2-30 Dec 2024
Fluorescent TG2/LRP1 substrate for imaging endocytosis
8080 MS 4322 Dec 2024
Selective PRMT5 Degrader (PROTAC®)
8830 CD22L-N3 (BPC-Sia-LacNAc-N3) Dec 2024
CD22L ligand with azide group for onward chemistry
8168 DHC-156 Dec 2024
Brachyury down modulator
8815 PA Janelia Fluor® 646, Haloalkane Dec 2024
Photoactivatable Janelia Fluor® 646 with chloroalkane handle for self-labeling tags fusion protein
8113 BAY 593 Dec 2024
Geranylgeranyltransferase-I (GGTase-I) inhibitor
8856 NX 5948 Dec 2024
Potent and selective BTK Degrader (PROTAC®)
8807 Janelia Fluor® 585, Haloalkane Nov 2024
Cell-permeable fluorogenic fluorescent dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate
8806 Janelia Fluor® 549, Haloalkane Nov 2024
Cell-permeable fluorogenic fluorescent dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate
8824 PDEδ ATTEC 12C Nov 2024
PDEδ autophagy-tethering compound (ATTEC) Degrader
8805 Janelia Fluor® 525, Haloalkane Nov 2024
Cell-permeable fluorogenic fluorescent dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate
TB0695-RMU Retinoic acid Nov 2024
Retinoic acid synthesized to Ancillary Material Grade
7496 FMK 9a Nov 2024
Potent ATG4B/autophagin-1 inhibitor; also inhibits calpain and cathepsin B
8073 MS 6105 Nov 2024
Potent lactate dehydrogenase Degrader (PROTAC®)
8018 142D6 Nov 2024
Potent Lys-covalent pan-IAP inhibitor
8809 Janelia Fluor® 646, Haloalkane Oct 2024
Cell-permeable fluorogenic fluorescent dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate
8808 Janelia Fluor® 635, Haloalkane Oct 2024
Cell-permeable fluorogenic fluorescent dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate
8010 SB 24011 Oct 2024
Inhibitor of STING-TRIM29 interaction; increases cellular STING levels
8152 JQ dS-4 Oct 2024
BRG1/SMARCA4 Degrader (PROTAC®)
8160 JFX™ 554, Maleimide Oct 2024
Deuterated Janelia Fluor® dye (Reactive group: Maleimide). Application: confocal microscopy, super-resolution microscopy (SRM) including dSTORM & STED. Suitable for live cell imaging
8813 RNA Imaging Probe 1c Oct 2024
Fluorogenic RNA imaging probe
8039 BI 3231 Oct 2024
Potent and selective hydroxysteroid 17β dehydrogenase 13 (HSD17B13) inhibitor
8170 CHIR 99021 in solution Oct 2024
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO
8162 JFX™ 650, Maleimide Oct 2024
Deuterated Janelia Fluor® dye (Reactive group: Maleimide). Application: confocal microscopy, super resolution microscopy (SRM) including dSTORM & STED. Suitable for live cell imaging
8093 Tazemetostat Sep 2024
Potent and selective EZH2 inhibitor
7959 LSN 3318839 Sep 2024
Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator
8151 VU 0542270 Sep 2024
Selective inhibitor of Kir6.1 KATP channels
8097 Janelia Fluor® 669, Maleimide Sep 2024
Red dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging
8008 MSC 4381 Sep 2024
Potent and selective monocarboxylate transporter 4 (MCT4) inhibitor
8175 NIBR LTSi Sep 2024
Potent and selective LATS inhibitor; activates YAP signaling
8163 JFX™ 650, NHS ester Sep 2024
Deuterated Janelia Fluor® dye (Reactive group: NHS ester). Application: confocal microscopy, super resolution microscopy (SRM) including dSTORM & STED. Suitable for live cell imaging
8079 MS 159 Sep 2024
NSD2 Degrader (PROTAC®)
8173 Adenosine 5'-(α,β-methylene)diphosphate disodium salt Aug 2024
Ecto-5'-nucleotidase (CD73) inhibitor
8150 LDN 193189 in solution Aug 2024
Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water
8045 FITC-CHIPOpt Aug 2024
Fluorescent CHIP/STUB1 E3 ligase inhibitor
8044 CHIPOpt Aug 2024
CHIP/STUB1 E3 ligase inhibitor
8095 LIH 383 Aug 2024
Atypical chemokine receptor (ACKR3) agonist
8134 Janelia Fluor® 635, Tetrazine Aug 2024
Red dye (Reactive group: tetrazine). Application: confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging
8126 Mpro Tracer Aug 2024
SARS-CoV-2 main protease fluorescent ligand; TR-FRET acceptor
7970 SAHA-FITC Aug 2024
Fluorescent HDAC1/2 probe; suitable for use in TR-FRET and FP assays
7900 SCOTfluor 510 Fmoc-Dapa-OH Jul 2024
Fmoc protected fluorescent amino acid for use in solid-phase peptide synthesis to prepare PAINT imaging probes
8083 JPS016 Jul 2024
Selective class I HDAC Degrader (PROTAC®)
8117 CoraFluor™ 1, thiol reactive Jul 2024
Terbium cryptate FRET donor for TR-FRET assay development, cysteine reactive for conjugation
8069 XIAP Tracer mF-Smac Jul 2024
Fluorescein labeled XIAP ligand for TR-FRET assay development
8077 MS 147 Jul 2024
PRC1 Degrader (PROTAC®); degrades BMI1 and RING1B
8023 AZ 14145845 Jul 2024
Dual Mer/Axl inhibitor
8143 GF-AFC Jul 2024
Cell permeable fluorogenic substrate cleaved by cytosolic aminopeptidases for non-lytic high throughput cell viability assays
8154 Janelia Fluor® 630b, Maleimide Jul 2024
Blinking fluorescent dye (Reactive group: maleimide). Application: super resolution microscopy (SRM) including SMLM
8155 Janelia Fluor® 630b, NHS ester Jul 2024
Blinking fluorescent dye (Reactive group: NHS ester). Application: super resolution microscopy (SRM) including SMLM
8076 MS 28 Jul 2024
Cyclin D1, CDK4/6 and cyclin D3 Degrader (PROTAC®)
7000 Y-27632 in solution Jul 2024
Sterile-filtered 10 mM solution of Y-27632 pre-dissolved in water
8174 PEI STAR-Go™ transfection reagent Jul 2024
Aqueous solution of polyethylenimine (PEI) transfection reagent
8118 UNC 8732 Jul 2024
Potent NSD2 Degrader
8156 Janelia Fluor® 635b, Maleimide Jul 2024
Blinking fluorescent dye (Reactive group: maleimide). Application: super resolution microscopy (SRM) including SMLM
8157 Janelia Fluor® 635b, NHS ester Jul 2024
Blinking fluorescent dye (Reactive group: NHS ester). Application: super resolution microscopy (SRM) including SMLM
8159 Janelia Fluor® 646b, NHS ester Jul 2024
Blinking fluorescent dye (Reactive group: NHS ester). Application: super resolution microscopy (SRM) including SMLM
7978 BAY 390 Jul 2024
Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable
8158 Janelia Fluor® 646b, Maleimide Jun 2024
Blinking fluorescent dye (Reactive group: maleimide). Application: super resolution microscopy (SRM) including SMLM
8122 MR 24 Jun 2024
Potent and selective MST3 kinase binding inhibitor
8103 dTAG Janelia Fluor® 585 Jun 2024
Fluorogenic srTAG probe for live cell imaging of FKBP12(F36V/L) fusion proteins
8102 dTAG Janelia Fluor® 525 Jun 2024
Fluorogenic srTAG probe for live cell imaging of FBKP12 (F36V/L) fusion proteins
8003 EN67, phenol Jun 2024
UBE2D degrader building block
7997 PAG 3'-piperazine-4-methylpiperidine Jun 2024
Cereblon ligand with terminal piperidine for onward chemistry
8084 JPS016NC Jun 2024
Negative control for JPS036 (Cat. No. 8085).