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Submit Review2-Methylthioadenosine triphosphate tetrasodium salt is a P2 purinoceptor agonist.
分子量 | 641.2 |
公式 | C11H14N5Na4O13P3S |
储存 | Store at -20°C |
纯度 | ≥98% (HPLC) |
CAS Number | 100020-57-3 |
PubChem ID | 16218831 |
InChI Key | UEEFBRHXFDJPTA-KWIZKVQNSA-J |
Smiles | NC1=C2C(N([C@@H]3O[C@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O)C=N2)=NC(SC)=N1.[Na+].[Na+].[Na+].[Na+] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
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溶解性 | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
参考文献是支持产品生物活性的出版物。
Burnstock et al (1983) Studies on the stereoselectivity of the P2-purinoreceptor. Br.J.Pharmacol. 79 907 PMID: 6317121
Cusack et al (1982) Specific but non-competitive inhibition by 2-alkylthioanalogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. Br.J.Pharmacol. 75 397 PMID: 7186826
Khakh et al (2001) International Union of Pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol.Rev. 53 107 PMID: 11171941
McMurray et al (1998) Purinoceptor subtypes mediating contraction and relaxation of marmoset urinary bladder smooth muscle. Br.J.Pharmacol. 123 1579 PMID: 9605564
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关键词: 2-Methylthioadenosine triphosphate tetrasodium salt, 2-Methylthioadenosine triphosphate tetrasodium salt supplier, P2, purinergic, agonists, P2X, Receptors, Purinergic, P2Y, purinoceptors, 2-Methylthio-ATP, 1062, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 2-Methylthioadenosine triphosphate tetrasodium salt 的部分引用包括:
Rahbar et al (2016) Purinergic and Cholinergic Drugs Mediate Hyperventilation in Zebrafish: Evidence from a Novel Chemical Screen. Nature 11 e0154261 PMID: 27100625
Zhang et al (2014) Agonist-bound structure of the human P2Y12 receptor. Med J Islam Repub Iran 509 119 PMID: 24784220
Nagai et al (2017) Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia. EBioMedicine 24 147 PMID: 28942281
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