2-Methylthioadenosine triphosphate tetrasodium salt

Pricing Availability   Qty
说明: Non-selective P2 agonist
别名: 2-Methylthio-ATP
化学名: 2-Methylthioadenosine-5'-triphosphate tetrasodium salt
纯度: ≥98% (HPLC)
说明书
引用文献 (3)
评论
文献 (1)

生物活性

2-Methylthioadenosine triphosphate tetrasodium salt is a P2 purinoceptor agonist.

技术数据

分子量 641.2
公式 C11H14N5Na4O13P3S
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 100020-57-3
PubChem ID 16218831
InChI Key UEEFBRHXFDJPTA-KWIZKVQNSA-J
Smiles NC1=C2C(N([C@@H]3O[C@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O)C=N2)=NC(SC)=N1.[Na+].[Na+].[Na+].[Na+]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据

溶解性 Soluble in water (supplied pre-dissolved at a concentration of 10mM)

产品说明书

分析证书/产品说明书
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参考文献

参考文献是支持产品生物活性的出版物。

Burnstock et al (1983) Studies on the stereoselectivity of the P2-purinoreceptor. Br.J.Pharmacol. 79 907 PMID: 6317121

Cusack et al (1982) Specific but non-competitive inhibition by 2-alkylthioanalogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. Br.J.Pharmacol. 75 397 PMID: 7186826

Khakh et al (2001) International Union of Pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol.Rev. 53 107 PMID: 11171941

McMurray et al (1998) Purinoceptor subtypes mediating contraction and relaxation of marmoset urinary bladder smooth muscle. Br.J.Pharmacol. 123 1579 PMID: 9605564


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关键词: 2-Methylthioadenosine triphosphate tetrasodium salt, 2-Methylthioadenosine triphosphate tetrasodium salt supplier, P2, purinergic, agonists, P2X, Receptors, Purinergic, P2Y, purinoceptors, 2-Methylthio-ATP, 1062, Tocris Bioscience

3 篇 2-Methylthioadenosine triphosphate tetrasodium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 2-Methylthioadenosine triphosphate tetrasodium salt 的部分引用包括:

Rahbar et al (2016) Purinergic and Cholinergic Drugs Mediate Hyperventilation in Zebrafish: Evidence from a Novel Chemical Screen. Nature 11 e0154261 PMID: 27100625

Zhang et al (2014) Agonist-bound structure of the human P2Y12 receptor. Med J Islam Repub Iran 509 119 PMID: 24784220

Nagai et al (2017) Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia. EBioMedicine 24 147 PMID: 28942281


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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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P2X and P2Y Receptors Scientific Review

P2X and P2Y Receptors Scientific Review

Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.