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2-MPMDQ

Cat. No. 0661 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0661 has been discontinued.

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说明： Potent, selective α1 antagonist. Also σ2 ligand
化学名： 2-[[4-(2-Methoxyphenyl)piperazin-1-yl]methyl-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one
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生物活性 技术数据 说明书 参考文献

生物活性 for 2-MPMDQ

2-MPMDQ is a potent and selective α1-adrenoceptor antagonist; hypotensive.

技术数据 for 2-MPMDQ

分子量 405.5
公式 C23H27N5O2
储存 Store at RT
CAS Number 149847-77-8
PubChem ID 4534085
InChI Key OULFYKAESNCMFJ-UHFFFAOYSA-N
Smiles COC1=C(C=CC=C1)N1CCN(CC2CN3C(=N2)C2=CC=CC=C2N(C)C3=O)CC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for 2-MPMDQ

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化学品安全技术说明书

参考文献 for 2-MPMDQ

参考文献是支持产品生物活性的出版物。

Chern et al (1993) Studies on quinazolines. 2,3-Dihydroimidazo[1,2c]quinazoline derivatives. A novel class of potent and selective α1-adrenoceptor antagonists and antihypertensive agents. J.Med.Chem. 36 2196 PMID: 8101878

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关键词: 2-MPMDQ, 2-MPMDQ supplier, Potent, selective, α1-adrenoceptor, alpha1-adrenoceptor, a1-adrenoceptor, α1-adrenergic, alpha1-adrenergic, a1-adrenergic, antagonists, σ2, sigma2, ligand, Receptors, hypotensive, anti-hypertensive, Adrenergic, Alpha-1, 0661, Tocris Bioscience

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Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.