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Submit Review2-Phospho-L-ascorbic acid trisodium salt
说明： Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
化学名： 2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt
纯度： ≥95% (HPLC)
生物活性
2-Phospho-L-ascorbic acid trisodium salt is a stable ascorbic acid derivative used in cell culture; in combination with FGF-2, maintains differentiation potential in bone marrow-derived mesenchymal stem cells (MSC) through increased expression of HGF. Also exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine (Cat. No. 5619).
技术数据
| 分子量 | 322.05 |
| 公式 | C6H6Na3O9P |
| 储存 | Desiccate at RT |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 66170-10-3 |
| PubChem ID | 10990876 |
| InChI Key | VWCFDYSMDMCPLU-OFBPEYICSA-K |
| Smiles | [O-]C([C@]([C@@H](O)CO)([H])O1)=C(OP([O-])([O-])=O)C1=O.[Na+].[Na+].[Na+] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 32.2 | 100 |
制备储备液
以下数据基于产品分子量 322.05。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.11 mL | 15.53 mL | 31.05 mL |
| 5 mM | 0.62 mL | 3.11 mL | 6.21 mL |
| 10 mM | 0.31 mL | 1.55 mL | 3.11 mL |
| 50 mM | 0.06 mL | 0.31 mL | 0.62 mL |
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产品说明书
参考文献
参考文献是支持产品生物活性的出版物。
Falcon et al (2014) An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors. PLoS One 9 e106901 PMID: 25210890
Bae et al (2015) L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor. Growth Factors 33 71 PMID: 25714612
Li et al (2015) Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis. Sci.Rep. 5 9819 PMID: 25909282
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关键词: 2-Phospho-L-ascorbic acid trisodium salt, 2-Phospho-L-ascorbic acid trisodium salt supplier, Vitamin, C, L-Ascorbic, acid, derivative, stem, cells, culture, mesenchymal, cytoprotective, Antioxidants, Mesenchymal, Stem, Cells, 5778, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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