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2-TEDC

Cat. No. 0645 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： 5-, 12-, 15-Lipoxygenase inhibitor
化学名： 2-(1-Thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate
纯度： ≥99% (HPLC)
说明书
引用文献
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for 2-TEDC

2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC50 values are 0.09, 0.013 and 0.5 μM respectively).

技术数据 for 2-TEDC

分子量 315.34
公式 C16H13NO4S
储存 Desiccate at +4°C
纯度 ≥99% (HPLC)
CAS Number 132465-10-2
PubChem ID 6069552
InChI Key KCGLTUBCAGZLHP-XYOKQWHBSA-N
Smiles OC1=C(O)C=C(\C=C(/C#N)C(=O)OCCC2=CC=CS2)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 2-TEDC

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 100
ethanol 25

制备储备液 for 2-TEDC

以下数据基于产品分子量 315.34。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.17 mL 15.86 mL 31.71 mL
5 mM 0.63 mL 3.17 mL 6.34 mL
10 mM 0.32 mL 1.59 mL 3.17 mL
50 mM 0.06 mL 0.32 mL 0.63 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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参考文献 for 2-TEDC

参考文献是支持产品生物活性的出版物。

Cho et al (1991) Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 34 1503 PMID: 2016727

If you know of a relevant reference for 2-TEDC, please let us know.

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关键词: 2-TEDC, 2-TEDC supplier, 5-lipoxygenase, 12-lipoxygenase, 15-Lipoxygenase, inhibitors, inhibits, Oxygenases, Oxidases, 5-LOX, 12-LOX, 15-LOX, Lipoxygenase, 0645, Tocris Bioscience

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