22-Oxacalcitriol

Name: 22-Oxacalcitriol
Brand: Tocris Bioscience
SKU: 4160

Cat. No. 4160 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4160 has been discontinued.

View all Vitamin D Receptors products.

说明： Non-calcemic vitamin D₃ (Cat. No. 4156) analog

别名： Maxacalcitol

化学名： (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

纯度： ≥95% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for 22-Oxacalcitriol

22-Oxacalcitriol is a non-calcemic vitamin D₃ (Cat. No. 4156) analog and VDR ligand. Suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Exhibits similar effects to calcitriol (Cat. No. 2551) in osteoblast-like cells. Inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.

技术数据 for 22-Oxacalcitriol

分子量	418.61
公式	C₂₆H₄₂O₄
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	103909-75-7
PubChem ID	6398761
InChI Key	DTXXSJZBSTYZKE-ZDQKKZTESA-N
Smiles	C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](OCCC(C)(O)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for 22-Oxacalcitriol

分析证书/产品说明书

化学品安全技术说明书

参考文献 for 22-Oxacalcitriol

参考文献是支持产品生物活性的出版物。

Monier-Faugere et al (1999) 22-Oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. Kidney Int. 55 821 PMID: 10027919

Barroga et al (2000) Inhibitory effects of 22-oxa-calcitriol and all-trans retinoic acid on the growth of a canine osteosarcoma derived cell-line in vivo and its pulmonary metastasis in vivo. Res.Vet.Sci. 68 79 PMID: 10684763

按标靶查看相关产品

Vitamin D Receptors

关键词: 22-Oxacalcitriol, 22-Oxacalcitriol supplier, 22-Oxacalcitriol, OCT, vitamin, D, analogue, analog, non-calcemic, VDR, Maxacalcitol, Vitamin, Receptors, 4160, Tocris Bioscience

篇 22-Oxacalcitriol 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 22-Oxacalcitriol 的引用文献。