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4-PPBP maleate

Cat. No. 0620 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0620 has been discontinued.

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说明： Specific σ ligand, NMDA antagonist
化学名： 4-Phenyl-1-(4-phenylbutyl)piperidine maleate
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for 4-PPBP maleate

4-PPBP maleate is a σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.

技术数据 for 4-PPBP maleate

分子量 409.52
公式 C21H27N.C4H4O4
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 201216-39-9
PubChem ID 11682970
InChI Key OASPNIMFGJVLES-BTJKTKAUSA-N
Smiles OC(=O)\C=C/C(O)=O.C(CCC1=CC=CC=C1)CN1CCC(CC1)C1=CC=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for 4-PPBP maleate

参考文献是支持产品生物活性的出版物。

Glennon et al (1991) Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 34 3360 PMID: 1662725

Whittemore et al (1997) Antagonism of N-MthD.-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326 PMID: 9223571

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关键词: 4-PPBP maleate, 4-PPBP maleate supplier, Specific, σ, sigma, ligand, NMDA, antagonists, Receptors, Sigma-Related, 0620, Tocris Bioscience

1 篇 4-PPBP maleate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 4-PPBP maleate 的部分引用包括：

Yang et al (2007) σ receptor agonists provide neuroprotection in vitro by preserving bcl-2. Front Behav Neurosci 104 1179 PMID: 17456670

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