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4-PPBP maleate

Cat. No. 0620 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Specific σ ligand, NMDA antagonist
化学名： 4-Phenyl-1-(4-phenylbutyl)piperidine maleate
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for 4-PPBP maleate

4-PPBP maleate is a σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.

技术数据 for 4-PPBP maleate

分子量 409.52
公式 C21H27N.C4H4O4
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 201216-39-9
PubChem ID 11682970
InChI Key OASPNIMFGJVLES-BTJKTKAUSA-N
Smiles OC(=O)\C=C/C(O)=O.C(CCC1=CC=CC=C1)CN1CCC(CC1)C1=CC=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 4-PPBP maleate

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
ethanol 10.24 25
DMSO 10.24 25

制备储备液 for 4-PPBP maleate

以下数据基于产品分子量 409.52。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.25 mM 9.77 mL 48.84 mL 97.68 mL
1.25 mM 1.95 mL 9.77 mL 19.54 mL
2.5 mM 0.98 mL 4.88 mL 9.77 mL
12.5 mM 0.2 mL 0.98 mL 1.95 mL

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参考文献 for 4-PPBP maleate

参考文献是支持产品生物活性的出版物。

Glennon et al (1991) Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 34 3360 PMID: 1662725

Whittemore et al (1997) Antagonism of N-MthD.-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326 PMID: 9223571

If you know of a relevant reference for 4-PPBP maleate, please let us know.

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关键词: 4-PPBP maleate, 4-PPBP maleate supplier, Specific, σ, sigma, ligand, NMDA, antagonists, Receptors, Sigma-Related, 0620, Tocris Bioscience

1 篇 4-PPBP maleate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 4-PPBP maleate 的部分引用包括：

Yang et al (2007) σ receptor agonists provide neuroprotection in vitro by preserving bcl-2. Front Behav Neurosci 104 1179 PMID: 17456670

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