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5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative

Cat. No. 1527 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1527 has been discontinued.

说明： Precursor to 5-Iodo-A-85380 (Cat. No. 1518)
化学名： (2S)-2-[[[5-(Trimethylstannyl)-3-pyridinyl]oxy]methyl]-1-azetidinecarboxylic acid, t-butyl ester
纯度： ≥98% (HPLC)
说明书
引用文献
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文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性

5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative is a precursor to the highly potent and selective ligand for the α4β2 nicotinic receptor, 5-Iodo-A-85380 (Cat. No.1518). Suitable for radioiodination.

技术数据

分子量 427.11
公式 C17H28N2O3Sn
储存 Desiccate at -20°C
纯度 ≥98% (HPLC)
CAS Number 213766-21-3
PubChem ID 10574471
InChI Key HHNYNAVVSDTMQD-HZAYLZKLSA-N
Smiles O=C(N1[C@H](COC2=CC([Sn](C)(C)C)=CN=C2)CC1)OC(C)(C)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献

参考文献是支持产品生物活性的出版物。

Koren et al (1998) 2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling. J.Med.Chem. 41 3690 PMID: 9733494

Mukhin et al (2000) 5-Iodo-A-85380, an α4β2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol.Pharmacol. 57 642 PMID: 10692507

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关键词: 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative, 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative supplier, Precursor, α4β2, a4b2, Nicotinic, Receptors, Acetylcholine, nAChR, Non-Selective, Subtypes, Other, 5-Iodo-A-853805-trimethylstannyl, N-BOC, derivative, (Other, Subtypes), (a4b2), 1527, Tocris Bioscience

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