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Submit Review5-Oxo-ETE
Discontinued Product
1796 has been discontinued.
View all Leukotriene and Related Receptors products.
说明： Oxoeicosanoid receptor agonist
别名： 5-KETE
化学名： 5-Oxo-(6E,8Z,11Z,14Z)-6,8,11,14-eicosatetraenoic acid
纯度： ≥95% (HPLC)
生物活性 for 5-Oxo-ETE
Potent oxoeicosanoid (OXE) receptor agonist (EC50 = 0.33 nM). Chemoattractant for both neutrophils and eosinophils and induces transendothelial migration of eosinophils.
技术数据 for 5-Oxo-ETE
| 分子量 | 318.46 |
| 公式 | C20H30O3 |
| 储存 | Store at -80°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 106154-18-1 |
| Smiles | CCCCC\C=C/C\C=C/C\C=C/C=C/C(CCCC(O)=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 5-Oxo-ETE
参考文献 for 5-Oxo-ETE
参考文献是支持产品生物活性的出版物。
Powell et al (1994) Effects of phorbol myristate acetate on the synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human polymorphonuclear leukocytes. Biochemistry 33 3927 PMID: 8142396
Jones et al (2003) Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. Mol.Pharmacol. 63 471 PMID: 12606753
Patel et al (2008) Structural requirements for activation of the 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor: identification of a mead acid metabolite with potent agonist activity. J.Pharmacol.Exp.Ther. 325 698 PMID: 18292294
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关键词: 5-oxo-ETE, 5-oxo-ETE supplier, Oxoeicosanoid, receptor, agonists, Receptors, leukotrienes, eicosanoids, 5-KETE, Leukotriene, and, Related, 1796, Tocris Bioscience
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