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Submit Review9-AC is a Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI.
分子量 | 222.24 |
公式 | C15H10O2 |
储存 | Store at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 723-62-6 |
PubChem ID | 2201 |
InChI Key | XGWFJBFNAQHLEF-UHFFFAOYSA-N |
Smiles | OC(=O)C1=C2C=CC=CC2=CC2=CC=CC=C12 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Cabantchik and Greger (1992) Chemical probes for anion transporters of mammalian cell membranes. Am.J.Physiol. 262 C803-C827 PMID: 1566811
Gadsby et al (1995) The CFTR chloride channel of mammalian heart. Annu.Rev.Physiol. 57 387 PMID: 7539989
Pusch et al (2006) Channel or transporter? The CLC saga continues. Exp.Physiol. 91 149 PMID: 16179405
Estévez et al (2003) Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1. Neuron 38 47 PMID: 12691663
关键词: 9-AC, 9-AC supplier, Chloride, transport, inhibitors, inhibits, Cl-, Channels, CFTR, Other, 0963, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 9-AC 的部分引用包括:
Freeman et al (2013) Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors. Online J Biol Sci 110 103 PMID: 23576702
Li et al (2005) Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin. Antimicrob Agents Chemother 49 388 PMID: 15616319
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