A 410099.1 amide-PEG5-amine

Cat. No. 7221 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： IAP ligand with PEG linker and terminal amine for onward chemistry

化学名： tert-Butyl ((S)-1-(((S)-2-((2S,4S)-4-(17-amino-3,6,9,12,15-pentaoxaheptadecanamido)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate

纯度： ≥95% (HPLC)

生物活性技术数据说明书参考文献

生物活性 for A 410099.1 amide-PEG5-amine

A 410099.1 amide-PEG5-amine is a functionalized IAP ligand for PROTAC^® research and development; incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines for A 410099.1 amide-PEG5-amine

This product is provided for use in onward chemistry. Suitable solvents can be used.

技术数据 for A 410099.1 amide-PEG5-amine

分子量	861.09
公式	C₄₄H₇₂N₆O₁₁
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	2446474-11-7
InChI Key	WUQFDZYWJGAVJW-XQVCTUMGSA-N
Smiles	CN(C(OC(C)(C)C)=O)[C@H](C(N[C@H](C(N1C[C@@H](NC(COCCOCCOCCOCCOCCN)=O)C[C@H]1C(N[C@@H]2CCCC3=CC=CC=C23)=O)=O)C4CCCCC4)=O)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for A 410099.1 amide-PEG5-amine

分析证书/产品说明书

化学品安全技术说明书

参考文献 for A 410099.1 amide-PEG5-amine

参考文献是支持产品生物活性的出版物。

Tinworth et al (2019) PROTAC-mediated degradation of Bruton's tyrosine kinase is inhibited by covalent binding. ACS Chem.Biol. 14 342 PMID: 30807093

If you know of a relevant reference for A 410099.1 amide-PEG5-amine, please let us know.

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