α-Conotoxin EI

Name: α-Conotoxin EI
Brand: Tocris Bioscience
SKU: 3124

Cat. No. 3124 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3124 has been discontinued.

View all Nicotinic Receptors (Other Subtypes) products.

说明： α1β1δγ selective nAChR antagonist

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for α-Conotoxin EI

Selective antagonist of neuromuscular nicotinic receptors α1β1γδ. Displays selectivity for α/δ sites over α/γ sites in Torpedo.

许可信息

Sold under license from University of Utah

技术数据 for α-Conotoxin EI

分子量	2093.4
公式	C₈₃H₁₂₅N₂₇O₂₇S₅
序列	RDXCCYHPTCNMSNPQIC (Modifications: X = Hyp, Cys-18 = C-terminal amide, Disulfide bridge between 4 - 10, 5 - 17)
储存	Store at -20°C
CAS Number	170663-33-9
PubChem ID	90488801
InChI Key	ZUOKYBVKCMQKIN-MLWUHNSQSA-N
Smiles	[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC3=CNC=N3)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(N)=O)NC2=O)[C@@H](C)CC)C(N)=O)NC1=O)[C@@H](C)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for α-Conotoxin EI

分析证书/产品说明书

化学品安全技术说明书

参考文献 for α-Conotoxin EI

参考文献是支持产品生物活性的出版物。

Martinez et al (1995) α-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity. Biochemistry 34 14519 PMID: 7578057

Park et al (2001) Solution conformation of α-Conotoxin EI, a neuromuscular toxin specific for the α1/δ subunit interface of Torpedo nicotinic acetylcholine receptor. J.Biol.Chem. 276 49028 PMID: 11641403

Lopez-Vera et al (2007) Novel α-conotoxins from Conus spurius and the α-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors. FEBS Lett. 274 3972

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关键词: alpha-Conotoxin EI, alpha-Conotoxin EI supplier, α1β1δγ, alpha1beta1deltagamma, a1b1dg, selective, nAChR, antagonists, Acetylcholine, Nicotinic, Receptors, Non-Selective, Subtypes, Other, α-conotoxin, alpha-conotoxin, EI, a-ConotoxinEI, conotoxins, venoms, (Other, Subtypes), 3124, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Nicotinic ACh Receptors Scientific Review

Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.