α-Conotoxin PnIA

Name: α-Conotoxin PnIA
Brand: Tocris Bioscience
SKU: 3123

Cat. No. 3123 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3123 has been discontinued.

View all Nicotinic Receptors (Other Subtypes) products.

说明： Selective α3β2 nAChR antagonist

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for α-Conotoxin PnIA

α-Conotoxin PnIA is a selective antagonist of α3β2 nAChR receptors (IC₅₀ values are 9.56 and 252 nM for α3β2 and α7 receptors respectively).

许可信息

Sold under license from University of Utah

技术数据 for α-Conotoxin PnIA

分子量	1622.82
公式	C₆₅H₉₅N₁₉O₂₂S₄
序列	GCCSLPPCAANNPDYC (Modifications: Cys-16 = C-terminal amide, Disulfide bridge between 2 - 8, 3 - 16)
储存	Desiccate at -20°C
CAS Number	705300-84-1
PubChem ID	73755066
InChI Key	VUVGEYBNLLGGBG-MVPSLEAZSA-N
Smiles	[H]NCC(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC2=O)C(N)=O)NC1=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for α-Conotoxin PnIA

分析证书/产品说明书

化学品安全技术说明书

参考文献 for α-Conotoxin PnIA

参考文献是支持产品生物活性的出版物。

Fainzilber et al (1994) New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors. Biochemistry 33 9523 PMID: 8068627

Luo et al (1999) Single-residue alteration in α-conotoxin PnIA switches its nAChR subtype selectivity. Biochemistry 38 14542 PMID: 10545176

Everhart et al (2003) Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors. J.Pharmacol.Exp.Ther. 306 664 PMID: 12734390

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关键词: alpha-Conotoxin PnIA, alpha-Conotoxin PnIA supplier, Selective, α3β2, alpha3beta2, a3b2, nAChR, antagonists, Acetylcholine, Nicotinic, Receptors, Non-Selective, Subtypes, Other, α-conotoxin, alpha-conotoxin, PnIA, conotoxins, venoms, (Other, Subtypes), 3123, Tocris Bioscience

篇 α-Conotoxin PnIA 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 α-Conotoxin PnIA 的引用文献。