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Submit ReviewAcamprosate calcium
说明： GABA agonist; also glutamatergic modulator
别名： Calcium acetylhomotaurinate
化学名： 3-(Acetylamino)-1-propanesulfonic acid hemicalcium salt
生物活性 for Acamprosate calcium
Acamprosate calcium is a GABA receptor agonist and modulator of glutamatergic systems. Reduces alcohol consumption in animal models of alcohol addiction.
技术数据 for Acamprosate calcium
| 分子量 | 200.24 |
| 公式 | C5H10NO4S.½ Ca |
| 储存 | Desiccate at RT |
| CAS Number | 77337-73-6 |
| PubChem ID | 155434 |
| InChI Key | BUVGWDNTAWHSKI-UHFFFAOYSA-L |
| Smiles | CC(=O)NCCCS(=O)(=O)[O-].CC(=O)NCCCS(=O)(=O)[O-].[Ca+2] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Acamprosate calcium
参考文献 for Acamprosate calcium
参考文献是支持产品生物活性的出版物。
Spanagel et al (1996) Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur.J.Pharmacol. 305 39 PMID: 8813529
Berton et al (1998) Acamprosate enhances N-MthD.-aspartate receptor-mediated neurotransmission but inhibits presynaptic GABA(B) receptors in nucleus accumbens neurons. Alcohol Clin.Exp.Res. 22 183 PMID: 9514305
Popp and Lovinger (2000) Interaction of acampr. with ethanol and spermine on NMDA receptors in primary cultured neurons. Eur.J.Pharmacol. 394 221 PMID: 10771287
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关键词: Acamprosate calcium, Acamprosate calcium supplier, GABA, agonists, receptors, glutamate, modulators, metabotropic, mGlu, mGluR, ionotropic, systems, glutamatergics, Calcium, acetylhomotaurinate, Miscellaneous, Glutamate, 3618, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.