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Acetylcholine chloride

Cat. No. 2809 5 篇引用文献 2 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Endogenous neurotransmitter
化学名： 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride
说明书
引用文献 (5)
评论 (2)
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Acetylcholine chloride

Acetylcholine chloride is an endogenous neurotransmitter. Acts at nicotinic and muscarinic acetylcholine receptors.

技术数据 for Acetylcholine chloride

分子量 181.66
公式 C7H16ClNO2
储存 Desiccate at RT
CAS Number 60-31-1
PubChem ID 6060
InChI Key JUGOREOARAHOCO-UHFFFAOYSA-M
Smiles CC(OCC[N+](C)(C)C)=O.[Cl-]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Acetylcholine chloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 18.17 100

制备储备液 for Acetylcholine chloride

以下数据基于产品分子量 181.66。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 5.5 mL 27.52 mL 55.05 mL
5 mM 1.1 mL 5.5 mL 11.01 mL
10 mM 0.55 mL 2.75 mL 5.5 mL
50 mM 0.11 mL 0.55 mL 1.1 mL

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产品说明书 for Acetylcholine chloride

分析证书/产品说明书
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化学品安全技术说明书

参考文献 for Acetylcholine chloride

参考文献是支持产品生物活性的出版物。

Wessler et al (1999) The cholinergic 'pitfall': acetylcholine, a universal cell molecule in biological systems, including humans. Clin.Exp.Pharmacol.Physiol. 26 198 PMID: 10081614

If you know of a relevant reference for Acetylcholine chloride, please let us know.

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查看全部 Nicotinic Receptor (Non-selective) Agonists

关键词: Acetylcholine chloride, Acetylcholine chloride supplier, Endogenous, neurotransmitter, Acetylcholine, Nicotinic, Receptors, Non-Selective, Subtypes, nAChR, Muscarinic, (Non-selective), Non-selective, Muscarinics, 2809, Tocris Bioscience

5 篇 Acetylcholine chloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Acetylcholine chloride 的部分引用包括：

Paniello et al (2018) Improved adductor function after canine recurrent laryngeal nerve injury and repair using muscle progenitor cells. Laryngoscope 128 E241 PMID: 29219186

Halum et al (2014) Stem cell-derived tissue-engineered constructs for hemilaryngeal reconstruction. Ann Otol Rhinol Laryngol 123 124 PMID: 24574468

Lee and Kim (2019) Basal Forebrain Cholinergic-induced Activation of Cholecystokinin Inhibitory Neurons in the Basolateral Amygdala. Exp Neurobiol 28 320 PMID: 31308792

Deng et al (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods 68 323 PMID: 23933114

Fairless et al (2013) Membrane potential measurements of isolated neurons using a voltage-sensitive dye. PLoS One 8 e58260 PMID: 23516458

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Acetylcholine chloride induces aortic ring relaxation.
By Chintan Koyani on 10/22/2018
分析类型： In Vivo
种属： Mouse
细胞系/组织： Aortic ring

C57BL6 mice were administered with LPS (5 mg/kg) alone or in combination with Empagliflozin (1 µM) for 16 h. Afterwards mice were sacrificed and aortic rings were isolated. Norepinephrine pre-contracted rings were incubated with indicated (in Image) concentrations of Acetylcholine chloride (ACh) to follow endothelial relaxation.

review image
Quantification of acetylcholine in tissue by LC-MS/MS..
By Olga Malysheva on 01/04/2018
分析类型： In Vitro
种属： Mouse

We used it as an analytical standard for quantification of acetylcholine in brain tissue.

Even 10mM solution does degrades in the -80C freezer. We keep our stock as 100mM and make new every 6 months.

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Nicotinic ACh Receptors Scientific Review

Nicotinic ACh Receptors Scientific Review

Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.