Amperozide hydrochloride

Name: Amperozide hydrochloride
Brand: Tocris Bioscience
SKU: 2746

Cat. No. 2746 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2746 has been discontinued.

View all Non-selective 5-HT<sub>2</sub> products.

说明： Atypical antipsychotic; high affinity 5-HT₂ ligand

别名： FG 5606

化学名： 4-[4,4-bis(4-Fluorophenyl)butyl]-N-ethyl-1-piperazinecarboxamide hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Amperozide hydrochloride

Atypical antipsychotic that displays high affinity for 5-HT₂ receptors (K_i = 26 nM) and low affinity for D₂ receptors. Supresses ethanol drinking in genetically ethanol-preferring rats.

技术数据 for Amperozide hydrochloride

分子量	437.95
公式	C₂₃H₂₉F₂N₃O.HCl
储存	Store at +4°C
纯度	≥99% (HPLC)
CAS Number	86725-37-3
Smiles	FC1=CC=C(C(C3=CC=C(F)C=C3)CCCN2CCN(C(NCC)=O)CC2)C=C1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Amperozide hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Amperozide hydrochloride

参考文献是支持产品生物活性的出版物。

Haskins et al (1987) Biochemical and electrophysical studies of the psychotropic compound, amperozide. Brain Res.Bull. 19 465 PMID: 2825928

Meltzer et al (1992) Effect of amperozide on rat cortical 5-HT₂ and striatal and limbic DA D₂ receptor occupancy: implications for antipsychotic action. Eur.J.Pharmacol. 216 67 PMID: 1388121

Myers et al (1993) 5-HT₂ receptor blockade by amperozide suppresses ethanol drinking in genetically preferring rats. Pharmacol.Biochem.Behav. 45 741 PMID: 8332634

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