AMT hydrochloride

Pricing Availability   Qty
说明: Potent, selective iNOS inhibitor
化学名: 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride
说明书
引用文献 (5)
评论

生物活性 for AMT hydrochloride

AMT hydrochloride is a potent, selective and reversible inhibitor of iNOS (IC50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).

技术数据 for AMT hydrochloride

分子量 166.67
公式 C5H10N2S.HCl
储存 Desiccate at +4°C
CAS Number 21463-31-0
PubChem ID 2733501
InChI Key HVJCRMIQAMEJNM-UHFFFAOYSA-N
Smiles NC1=NCCC(S1)C.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for AMT hydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 10

制备储备液 for AMT hydrochloride

以下数据基于产品分子量 166.67。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 60 mL 299.99 mL 599.99 mL
0.5 mM 12 mL 60 mL 120 mL
1 mM 6 mL 30 mL 60 mL
5 mM 1.2 mL 6 mL 12 mL

Molarity Calculator

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产品说明书 for AMT hydrochloride

分析证书/产品说明书
选择另一批次:

参考文献 for AMT hydrochloride

参考文献是支持产品生物活性的出版物。

Liao et al (2006) Nitric oxide signaling in stretch-induced apoptosis of neonatal rat cardiomyocytes. FASEB J. 20 E1196 PMID: 16877524

Nakane et al (1995) Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol.Pharmacol. 47 831 PMID: 7536889

Yu et al (2005) Inhibition of sarcoplasmic reticular function by chronic interleukin-6 exposure via iNOS in adult ventricular myocytes. J.Physiol. 566 327 PMID: 15845578


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关键词: AMT hydrochloride, AMT hydrochloride supplier, Potent, selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, 0871, Tocris Bioscience

5 篇 AMT hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 AMT hydrochloride 的部分引用包括:

Lee et al (2018) Ginsenosides from Korean Red Ginseng ameliorate lung inflammatory responses: inhibition of the MAPKs/NF-κB/c-Fos pathways. J Ginseng Res 42 476 PMID: 30337808

Lee et al (2016) Inhibition of Lung Inflammation by Acanthopanax divaricatus var. Albeofructus and Its Constituents. PLoS One 24 67 PMID: 26759704

Wong et al (2017) Role of inducible nitric oxide synthase in endothelium-independent relaxation to RLX in rat aorta. Br J Pharmacol 174 718 PMID: 28138957

Messlinger et al (2000) Involvement of nitric oxide in the modulation of dural arterial blood flow in the rat. Br J Pharmacol 129 1397 PMID: 10742295


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