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Angiotensin (1-7)

Cat. No. 1562 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Vasorelaxant peptide
别名： [Ile5]Angiotensin I (1-7),Ang-(1-7)
纯度： ≥95% (HPLC)
说明书
引用文献 (1)
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Angiotensin (1-7)

Angiotensin (1-7) is an endogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.

技术数据 for Angiotensin (1-7)

分子量 899
公式 C41H62N12O11
序列 DRVYIHP
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 51833-78-4
PubChem ID 123805
InChI Key PVHLMTREZMEJCG-GDTLVBQBSA-N
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Angiotensin (1-7)

溶解性 Soluble to 1 mg/ml in water

产品说明书 for Angiotensin (1-7)

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参考文献 for Angiotensin (1-7)

参考文献是支持产品生物活性的出版物。

Lemos et al (2002) Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats. Br.J.Pharmacol. 135 1743 PMID: 11934815

Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45 PMID: 10967201

Santos et al (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc.Natl.Acad.Sci.U.S.A. 100 8258 PMID: 12829792

If you know of a relevant reference for Angiotensin (1-7), please let us know.

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关键词: Angiotensin (1-7), Angiotensin (1-7) supplier, Vasorelaxant, peptide, AT, Receptors, Non-Selective, Angiotensin, agonists, Mas, [Ile5]Angiotensin, I, (1-7), Ang-(1-7), Non-selective, 1562, Tocris Bioscience

1 篇 Angiotensin (1-7) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Angiotensin (1-7) 的部分引用包括：

Pan et al (2018) FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1-7) Axis in Mice. Cell Metab 27 1323 PMID: 29706566

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