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Submit ReviewAniracetam
说明： Inhibits desensitization; AMPA > kainate
化学名： 1-(4-Methoxybenzoyl)-2-pyrrolidinone
纯度： ≥99% (HPLC)
生物活性 for Aniracetam
Aniracetam is a nootropic, with modulatory actions through allosteric potentiation of AMPA specific receptors, reduction of glutamate receptor desensitization and potentiation of metabotropic glutamate receptor activity. Anxiolytic following systemic administration.
技术数据 for Aniracetam
| 分子量 | 219.24 |
| 公式 | C12H13NO3 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 72432-10-1 |
| PubChem ID | 2196 |
| InChI Key | ZXNRTKGTQJPIJK-UHFFFAOYSA-N |
| Smiles | COC1=CC=C(C=C1)C(=O)N1CCCC1=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Aniracetam
参考文献 for Aniracetam
参考文献是支持产品生物活性的出版物。
Isaacson and Nicholl (1991) Aniracetam reduces glutamate receptor desensitisation and slows the decay of fast excitatory synaptic currents in the hippocampus. Proc.Natl.Acad.Sci.U.S.A. 88 10936 PMID: 1660156
Ito et al (1990) Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. J.Physiol. 424 553 PMID: 1975272
Nakamura and Kurasawa (2001) Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur.J.Pharmacol. 420 33 PMID: 11412837
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关键词: Aniracetam, Aniracetam supplier, Desensitization, inhibitors, inhibits, AMPA, kainate, Glutamate, Receptors, iGluR, Ionotropic, allosteric, modulators, potentiators, 0867, Tocris Bioscience
1 篇 Aniracetam 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Aniracetam 的部分引用包括：
Moldavan and Allen (2010) Retinohypothalamic tract synapses in the rat suprachiasmatic nucleus demonstrate short-term synaptic plasticity. J Neurophysiol 103 2390 PMID: 20220078
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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