Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewAPcK 110
说明： KIT inhibitor
化学名： 6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine
纯度： ≥98% (HPLC)
生物活性 for APcK 110
KIT inhibitor; inhibits phosphorylation of KIT, STAT3, STAT5 and Akt. Suppresses proliferation of OCI/AML3 cells (IC50 = 175 nM). Caspase-dependant apoptosis inducer.
技术数据 for APcK 110
| 分子量 | 349.36 |
| 公式 | C20H16FN3O2 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 1001083-74-4 |
| PubChem ID | 24786010 |
| InChI Key | CAMGZGMEPKFVMF-UHFFFAOYSA-N |
| Smiles | FC(C=C3)=CC=C3C1=NNC2=C1C=CC(C4=CC(OC)=CC(OC)=C4)=N2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for APcK 110
参考文献 for APcK 110
参考文献是支持产品生物活性的出版物。
Faderl et al (2009) Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer Res. 69 3910 PMID: 19383925
按产品操作查看相关产品
关键词: APcK 110, APcK 110 supplier, APcK110, Kit, inhibitors, inhibits, Other, RTKs, 3704, Tocris Bioscience
APcK 110 的评论
目前没有该产品的评论。 Be the first to review APcK 110 and earn rewards!
Have you used APcK 110?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image