Apelin-17 (human, bovine)

Discontinued Product

3007 has been discontinued.

View all Apelin Receptors products.
说明: Endogenous apelin agonist
别名: K17F,Prepro-61-77-Apelin
纯度: ≥95% (HPLC)
说明书
引用文献 (1)
评论

生物活性 for Apelin-17 (human, bovine)

Apelin-17 (human, bovine) is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).

技术数据 for Apelin-17 (human, bovine)

分子量 2138.56
公式 C96H156N34O20S
序列 KFRRQRPRLSHKGPMPF
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 217082-57-0
PubChem ID 16130452
InChI Key SVWSKJCJNAIKNH-MJZUAXFLSA-N
Smiles [H]N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Apelin-17 (human, bovine)

分析证书/产品说明书
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参考文献 for Apelin-17 (human, bovine)

参考文献是支持产品生物活性的出版物。

Medhurst et al (2003) Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J.Neurochem. 84 1162 PMID: 12603839

Tatemoto et al (1998) Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem.Biophys.Res.Comms. 251 471

De Mota et al (2004) Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release. Proc.Natl.Acad.Sci. USA 101 10464

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关键词: Apelin-17 (human, bovine), Apelin-17 (human, bovine) supplier, Endogenous, APJ, receptor, agonists, Receptors, Apelin, adipokines, K17F, Prepro-61-77-Apelin, 3007, Tocris Bioscience

1 篇 Apelin-17 (human, bovine) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Apelin-17 (human, bovine) 的部分引用包括:

Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888


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