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ASP 9521

Cat. No. 6084 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6084 has been discontinued.

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说明： Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable
化学名： [4-(2-Hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)methanone
纯度： ≥98% (HPLC)
说明书
引用文献
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文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for ASP 9521

ASP 9521 is a potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor (IC50 = 11 - 49 nM). Suppresses androstenedione-dependent protein-specific antigen (PSA) production and cell proliferation in LNCaP cells in vitro. Orally bioavailable.

技术数据 for ASP 9521

分子量 330.42
公式 C19H26N2O3
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 1126084-37-4
PubChem ID 25210792
InChI Key OXSCPDKUZWPWFR-UHFFFAOYSA-N
Smiles O=C(N1CCC(CC1)CC(C)(O)C)C2=CC3=CC(OC)=CC=C3N2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for ASP 9521

参考文献是支持产品生物活性的出版物。

Kikuchi et al (2014) In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). Invest.New Drugs 32 860 PMID: 24981575

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关键词: ASP 9521, ASP 9521 supplier, ASP9521, 17beta, 17B, hydroxysteroid, dehydrogenase, type, 5, inhibitors, inhibits, 17β-HSD5, AK1RC3, potent, orally, bioavailable, Other, Dehydrogenases, 6084, Tocris Bioscience

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