ATPγS tetralithium salt

Cat. No. 4080 7 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Non-selective P2 agonist; analog of ATP (Cat. No. 3245)

别名： ATP-γS

化学名： Adenosine-5'-(γ-thio)-triphosphate tetralithium salt

纯度： ≥85% (HPLC)

引用文献 (7)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for ATPγS tetralithium salt

ATPγS tetralithium salt is a P2 purinergic receptor agonist. Nonhydrolyzable analog of ATP (Cat. No. 3245).

技术数据 for ATPγS tetralithium salt

分子量	546.98
公式	C₁₀H₁₂Li₄N₅O₁₂P₃S
储存	Store at -20°C
纯度	≥85% (HPLC)
CAS Number	93839-89-5
PubChem ID	5311341
InChI Key	DWQFDOIBOYDYKH-KWIZKVQNSA-J
Smiles	NC1=C2C(N([C@@H]3O[C@H](COP(OP(OP([O-])([O-])=S)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O)C=N2)=NC=N1.[Li+].[Li+].[Li+].[Li+]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for ATPγS tetralithium salt

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	27.35	50

制备储备液 for ATPγS tetralithium salt

以下数据基于产品分子量 546.98。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.5 mM	3.66 mL	18.28 mL	36.56 mL
2.5 mM	0.73 mL	3.66 mL	7.31 mL
5 mM	0.37 mL	1.83 mL	3.66 mL
25 mM	0.07 mL	0.37 mL	0.73 mL

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产品说明书 for ATPγS tetralithium salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for ATPγS tetralithium salt

参考文献是支持产品生物活性的出版物。

Evans et al (1995) Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2X purinoceptors). Mol.Pharmacol. 48 178 PMID: 7544432

Peck and Herschlag (2003) Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor elF4A. RNA 9 1180 PMID: 13130132

Chrysogelos et al (1983) The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate). J.Biol.Chem. 258 12624 PMID: 6313668

If you know of a relevant reference for ATPγS tetralithium salt, please let us know.

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关键词: ATPgammaS tetralithium salt, ATPgammaS tetralithium salt supplier, ATPgammaS, ATPγ, ATPgS, ATP, analogs, purinergic, receptors, p2x, p2y, purinoceptors, agonists, ATP-gS, ATP-yS, P2X, Receptors, Purinergic, P2Y, 4080, Tocris Bioscience

7 篇 ATPγS tetralithium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 ATPγS tetralithium salt 的部分引用包括：

Jean-Michel et al (2021) Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner. Elife 10 PMID: 34842136

Timothy S et al (2021) Differential Regulation of ATP- and UTP-Evoked Prostaglandin E2 and IL-6 Production from Human Airway Epithelial Cells. J Immunol 207 1275-1287 PMID: 34389624

Aho et al (2016) Extracellular ATP protects endothelial cells against DNA damage. Purinergic Signal 12 575 PMID: 27030122

Ke et al (2020) A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome. Cell Chem Biol 27 1073-1083.e12 PMID: 32521230

Handly & Wollman (2017) Wound-induced Ca²⁺ wave propagates through a simple release and diffusion mechanism. Mol Biol Cell 28 1457 PMID: 28404746

Miguel Cruz & Beall et al (2020) Extracellular ATP Increases Glucose Metabolism in Skeletal Muscle Cells in a P₂ Receptor Dependent Manner but Does Not Contribute to Palmitate-Induced Insulin Resistance Front Physiol 11 PMID: 33101053

Gault et al (2014) Osmotic surveillance mediates rapid wound closure through nucleotide release. J Cell Biol 207 767 PMID: 25533845

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