β-Pompilidotoxin

Discontinued Product

1539 has been discontinued.

View all Voltage-gated Sodium (Na<sub>V</sub>) Channels products.
说明: Slows neuronal Na+ channel inactivation
别名: β-PMTX
说明书
引用文献
评论

生物活性 for β-Pompilidotoxin

β-Pompilidotoxin is a novel wasp neurotoxin that slows Na+ channel inactivation. Facilitates neuromuscular synaptic transmission and discriminates between rat neuronal and cardiac Na+ channel α-subunits.

许可信息

Sold with the permission of Suntory Ltd.

技术数据 for β-Pompilidotoxin

分子量 1557.9
公式 C71H124N22O17
序列 RIKIGLFDQLSRL

(Modifications: Leu-13 = C-terminal amide)

储存 Desiccate at -20°C
CAS Number 216064-36-7
PubChem ID 90479801
InChI Key YBOJYGJMKPMNRC-QRIWDNSUSA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for β-Pompilidotoxin

分析证书/产品说明书
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参考文献 for β-Pompilidotoxin

参考文献是支持产品生物活性的出版物。

Kinoshita et al (2001) Novel wasp toxin discriminates between neuronal and cardiac sodium channels. Mol.Pharmacol. 59 1457 PMID: 11353806

Konno et al (1998) Isolation and structure of pompilidotoxins, novel peptide neurotoxins in solitary wasp venoms. Biochem.Biophys.Res.Commun. 250 612 PMID: 9784394

Miyawaki et al (2002) Differential effects of novel wasp toxin on rat hippocampal interneurons. Neurosci.Lett. 328 25 PMID: 12123851

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