Betaxolol hydrochloride

Cat. No. 0906 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Selective β₁ antagonist

化学名： 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanol hydrochloride

纯度： ≥99% (HPLC)

引用文献 (5)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Betaxolol hydrochloride

Betaxolol hydrochloride is a selective β₁-adrenoceptor antagonist.

技术数据 for Betaxolol hydrochloride

分子量	343.89
公式	C₁₈H₂₉NO₃.HCl
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	63659-19-8
PubChem ID	107952
InChI Key	CHDPSNLJFOQTRK-UHFFFAOYSA-N
Smiles	Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Betaxolol hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	17.19	50

制备储备液 for Betaxolol hydrochloride

以下数据基于产品分子量 343.89。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.5 mM	5.82 mL	29.08 mL	58.16 mL
2.5 mM	1.16 mL	5.82 mL	11.63 mL
5 mM	0.58 mL	2.91 mL	5.82 mL
25 mM	0.12 mL	0.58 mL	1.16 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

产品说明书 for Betaxolol hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Betaxolol hydrochloride

参考文献是支持产品生物活性的出版物。

Beresford and Heel (1986) Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension. Drugs 31 6 PMID: 2866947

Satoh et al (1993) The affinity of betaxolol, a β₁-adrenoceptor-selective blocking agent, for β-adrenoceptors in the bovine trachea and heart Br.J.Pharmacol. 108 484 PMID: 8383566

Setoguchi et al (1995) Inhibitory action of betaxolol, a β₁-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea pig artery and vein. Br.J.Pharmacol. 115 198 PMID: 7647977

Merck Index 12 1229

If you know of a relevant reference for Betaxolol hydrochloride, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Adrenergic β₁ Receptor Antagonists

关键词: Betaxolol hydrochloride, Betaxolol hydrochloride supplier, Selective, α1-adrenoceptor, beta1-adrenoceptor, β1-Adrenergic, beta1-Adrenergic, b1-adrenoceptor, b1-adrenergic, antagonists, receptors, Adrenergic, Beta-1, Receptors, 0906, Tocris Bioscience

5 篇 Betaxolol hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Betaxolol hydrochloride 的部分引用包括：

Meitzen et al (2011) β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem 116 984 PMID: 21143600

Schutsky et al (2011) Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling. J Neurosci 31 14172 PMID: 21976502

Nobis et al (2011) β-Adrenergic receptors enhance excitatory transmission in the bed nucleus of the stria terminalis through a corticotrophin-releasing factor receptor-dependent and cocaine-regulated mechanism. Biol Psychiatry 69 1083 PMID: 21334600

Littmann et al (2015) Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands. Cardiovasc Res 355 183 PMID: 26306764

Nackley et al (2007) Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain 128 199 PMID: 17084978

您是否知道使用了 Tocris Betaxolol hydrochloride 的优秀论文？请告知我们.