Betaxolol hydrochloride

Name: Betaxolol hydrochloride
Brand: Tocris Bioscience
SKU: 0906

Cat. No. 0906 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0906 has been discontinued.

View all Adrenergic β<sub>1</sub> Receptors products.

说明： Selective β₁ antagonist

化学名： 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanol hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献 (5)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Betaxolol hydrochloride

Betaxolol hydrochloride is a selective β₁-adrenoceptor antagonist.

技术数据 for Betaxolol hydrochloride

分子量	343.89
公式	C₁₈H₂₉NO₃.HCl
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	63659-19-8
PubChem ID	107952
InChI Key	CHDPSNLJFOQTRK-UHFFFAOYSA-N
Smiles	Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Betaxolol hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Betaxolol hydrochloride

参考文献是支持产品生物活性的出版物。

Beresford and Heel (1986) Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension. Drugs 31 6 PMID: 2866947

Satoh et al (1993) The affinity of betaxolol, a β₁-adrenoceptor-selective blocking agent, for β-adrenoceptors in the bovine trachea and heart Br.J.Pharmacol. 108 484 PMID: 8383566

Setoguchi et al (1995) Inhibitory action of betaxolol, a β₁-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea pig artery and vein. Br.J.Pharmacol. 115 198 PMID: 7647977

Merck Index 12 1229

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关键词: Betaxolol hydrochloride, Betaxolol hydrochloride supplier, Selective, α1-adrenoceptor, beta1-adrenoceptor, β1-Adrenergic, beta1-Adrenergic, b1-adrenoceptor, b1-adrenergic, antagonists, receptors, Adrenergic, Beta-1, Receptors, 0906, Tocris Bioscience

5 篇 Betaxolol hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Betaxolol hydrochloride 的部分引用包括：

Meitzen et al (2011) β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem 116 984 PMID: 21143600

Schutsky et al (2011) Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling. J Neurosci 31 14172 PMID: 21976502

Nobis et al (2011) β-Adrenergic receptors enhance excitatory transmission in the bed nucleus of the stria terminalis through a corticotrophin-releasing factor receptor-dependent and cocaine-regulated mechanism. Biol Psychiatry 69 1083 PMID: 21334600

Littmann et al (2015) Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands. Cardiovasc Res 355 183 PMID: 26306764

Nackley et al (2007) Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain 128 199 PMID: 17084978