Biperiden hydrochloride

Name: Biperiden hydrochloride
Brand: Tocris Bioscience
SKU: 2853

Cat. No. 2853 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2853 has been discontinued.

View all M<sub>1</sub> Receptors products.

说明： Muscarinic receptor antagonist; some selectivity for M₁

别名： Akineton

化学名： α-Bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-1-piperidinepropanol hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Biperiden hydrochloride

Biperiden hydrochloride is a muscarinic receptor antagonist that displays some selectivity for the M₁ subtype (K_i values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M₁, M₄, M₃, M₂ and M₅ receptors respectively). Alleviates extrapyramidal symptoms associated with antipsychotic drugs. Displays antiparkinsonian activity.

技术数据 for Biperiden hydrochloride

分子量	347.92
公式	C₂₁H₂₉NO.HCl
储存	Desiccate at +4°C
纯度	≥99% (HPLC)
CAS Number	1235-82-1
PubChem ID	92151
InChI Key	RDNLAULGBSQZMP-UHFFFAOYSA-N
Smiles	OC(CCN3CCCCC3)(C4=CC=CC=C4)C1CC2C=CC1C2.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Biperiden hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Biperiden hydrochloride

参考文献是支持产品生物活性的出版物。

Bolden et al (1992) Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in chinese hamster ovary cells. J.Pharmacol.Exp.Ther. 260 576 PMID: 1346637

Sudo et al (1999) Muscarinic receptor occupancy by bipe. in living human brain. Life Sci. 64 PL99 PMID: 10069534

Brocks (1999) Anticholinergic drugs used in Parkinson's disease: an overlooked class of drugs from a pharmacokinetic perspective. J.Pharm.Pharmaceut.Sci. 2 39

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关键词: Biperiden hydrochloride, Biperiden hydrochloride supplier, Muscarinic, receptor, antagonists, selectivity, M1, Receptors, Acetylcholine, ACh, Akineton, 2853, Tocris Bioscience

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