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Submit ReviewBNTX maleate
Discontinued Product
0899 has been discontinued.
说明： Standard δ1 selective antagonist
化学名： 7-Benzylidenenaltrexone maleate
纯度： ≥99% (HPLC)
生物活性 for BNTX maleate
BNTX maleate is a standard selective δ1 opioid receptor antagonist. Also inhibits neurogenic ion transport mediated by a putative novel opioid receptor in porcine ileal mucosa.
技术数据 for BNTX maleate
| 分子量 | 545.59 |
| 公式 | C27H27NO4.C4H4O4 |
| 储存 | Desiccate at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 864461-31-4 |
| PubChem ID | 71296994 |
| InChI Key | GKHUUKGUNNYVGB-LQDKARLYSA-N |
| Smiles | OC(=O)\C=C/C(O)=O.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)C\C(=C/C1=CC=CC=C1)C2=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BNTX maleate
参考文献 for BNTX maleate
参考文献是支持产品生物活性的出版物。
Hammond et al (1995) Antinociception and d-1 opioid receptors in the rat spinal cord: studies with intrathecal 7-benzylidenenaltrexone. J.Pharmacol.Exp.Ther. 274 1317 PMID: 7562504
Poonyachoti et al (2001) Pharmacological evidence for a 7-benzylidenenaltrexone-preferring opioid receptor mediating the inhibitory actions of peptidic δ- and μ-opioid agonists on neurogenic ion transport in porcine ileal mucosa. J.Pharmacol.Exp.Ther. 297 672 PMID: 11303057
Portoghese et al (1992) A δ1-opioid receptor antagonist: 7-benzylidenenaltrexone. Eur.J.Pharmacol. 218 195 PMID: 1327826
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关键词: BNTX maleate, BNTX maleate supplier, δ1-opioid, delta1-opioid, selective, antagonists, DOP, Receptors, OP1, Delta, Opioid, 0899, Tocris Bioscience
1 篇 BNTX maleate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 BNTX maleate 的部分引用包括：
Gomes et al (2000) Heterodimerization of μ and δ opioid receptors: A role in opiate synergy. J Cereb Blood Flow Metab 20 RC110 PMID: 11069979
BNTX maleate 的评论
平均评分: 5 (Based on 1 Review.)
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42 perturbagens used the zebrafish DASPEI screen.
By
Anonymous on 12/17/2019
分析类型： In Vivo
种属： Other
细胞系/组织： larvae
Zebrafish larvae were placed into 48-well plates and used the DASPEI screen by 42 perturbagens drugs, including this compound
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