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Submit ReviewBP 554 maleate is a selective 5-HT1A agonist.
分子量 | 456.48 |
公式 | C20H24N2O3.C4H4O4 |
储存 | Store at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 1221401-95-1 |
PubChem ID | 56972150 |
InChI Key | NBCXNOHQTALBRA-BTJKTKAUSA-N |
Smiles | OC(=O)\C=C/C(O)=O.C(COC1=CC=C2OCOC2=C1)CN1CCN(CC1)C1=CC=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Matsuda et al (1989) Agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (BP-554) at central 5-HT1A receptors. Eur.J.Pharmacol. 170 75 PMID: 2533078
关键词: BP 554 maleate, BP 554 maleate supplier, Selective, 5-HT1A, agonists, Serotonin, Receptors, 5-HT1, BP554, maleate, 0556, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 BP 554 maleate 的部分引用包括:
Huang et al (2009) Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. Br J Pharmacol 29 13909 PMID: 19890001
Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.