BQ 788 sodium salt

Cat. No. 1500 8 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Selective ET_B antagonist

化学名： N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine sodium salt

纯度： ≥95% (HPLC)

引用文献 (8)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for BQ 788 sodium salt

BQ 788 sodium salt is a potent, selective ET_B receptor antagonist (IC₅₀ = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells).

技术数据 for BQ 788 sodium salt

分子量	663.79
公式	C₃₄H₅₀N₅NaO₇
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	156161-89-6
PubChem ID	16759603
InChI Key	QCVIFBRTTLMEOV-FUKQNADPSA-M
Smiles	[Na+].CCCC[C@@H](NC(=O)[C@@H](CC1=CN(C(=O)OC)C2=C1C=CC=C2)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for BQ 788 sodium salt

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	3.32	5

制备储备液 for BQ 788 sodium salt

以下数据基于产品分子量 663.79。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.05 mM	30.13 mL	150.65 mL	301.3 mL
0.25 mM	6.03 mL	30.13 mL	60.26 mL
0.5 mM	3.01 mL	15.07 mL	30.13 mL
2.5 mM	0.6 mL	3.01 mL	6.03 mL

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产品说明书 for BQ 788 sodium salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for BQ 788 sodium salt

参考文献是支持产品生物活性的出版物。

Davenport (2002) International Union of Pharmacology. XXIX. Update on endothelin receptor nomenclature. Pharmacol.Rev. 54 219 PMID: 12037137

Ishikawa et al (1994) Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788. Proc.Natl.Acad.Sci.U.S.A. 91 4892 PMID: 8197152

Okada and Nishikibe (2002) BQ-788, a selective endothelin ET_B receptor antagonist. Cardiovasc.Drug Rev. 20 53 PMID: 12070534

If you know of a relevant reference for BQ 788 sodium salt, please let us know.

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