BRD 7116

Discontinued Product

5336 has been discontinued.

View all Cancer Stem Cells products.
说明: Inhibitor of leukemia stem cell activity
化学名: N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
纯度: ≥98% (HPLC)
说明书
引用文献
评论
文献 (5)

生物活性 for BRD 7116

Inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM). Exhibits >100-fold selectivity for LSCs over normal hematopoietic stem cells.

技术数据 for BRD 7116

分子量 496.66
公式 C28H36N2O4S
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 329059-55-4
PubChem ID 981129
InChI Key UHXFWAHRAMUDLJ-UHFFFAOYSA-N
Smiles O=C(C1C(C)(C)C1(C)C)NC(C=C2)=CC=C2S(C3=CC=C(NC(C4C(C)(C)C4(C)C)=O)C=C3)(=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for BRD 7116

参考文献是支持产品生物活性的出版物。

Hartwell et al (2013) Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat.Chem.Biol. 9 840 PMID: 24161946

按标靶查看相关产品

关键词: BRD 7116, BRD 7116 supplier, BRD7116, leukemia, stem, cells, inhibitors, inhibits, LSCs, Cancer, Stem, Cells, 5336, Tocris Bioscience

篇 BRD 7116 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 BRD 7116 的引用文献。

BRD 7116 的评论

目前没有该产品的评论。 Be the first to review BRD 7116 and earn rewards!

Have you used BRD 7116?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。


Epigenetics in Cancer Research Product Guide

Epigenetics in Cancer Research Product Guide

This product guide reviews some of the main areas in cancer epigenetics research and lists around 120 products that can be used for the main epigenetic targets including:

  • Histone Methylation
  • Histone Acetylation
  • DNA Methylation
  • Ubiquitination
  • Bromodomains
Stem Cell Research Product Guide

Stem Cell Research Product Guide

This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:

  • Self-renewal and Maintenance
  • Differentiation
  • Reprogramming
  • Organoid Generation
  • GMP and Ancillary Material Grade Products
Stem Cells Scientific Review

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cell Workflow Poster

Stem Cell Workflow Poster

Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.

Stem Cells Poster

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.