BTC

Discontinued Product

5421 has been discontinued.

View all Estrogen and Related Receptors products.
说明: Selective estrogen receptor modulator (SERM)
化学名: 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol
纯度: ≥99% (HPLC)
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引用文献
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生物活性 for BTC

Selective estrogen receptor modulator (SERM); induces regression of tamoxifen-resistant, hormone independent xenograft tumors. Displays no significant gain in uterine weight in treated mice.

技术数据 for BTC

分子量 242.29
公式 C14H10O2S
储存 Store at -20°C
纯度 ≥99% (HPLC)
CAS Number 63676-22-2
PubChem ID 445920
InChI Key MDGWZLQPNOETLH-UHFFFAOYSA-N
Smiles OC(C=C3)=CC=C3C2=CC1=CC=C(O)C=C1S2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for BTC

参考文献是支持产品生物活性的出版物。

Molloy et al (2014) Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer. Mol.Cancer.Ther. 13 2515 PMID: 25205655

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关键词: BTC, BTC supplier, oestrogen, receptors, modulators, SERM, tamoxifen, resistant, antitumor, antitumour, Estrogen, and, Related, Receptors, 5421, Tocris Bioscience

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Estrogen Signaling Pathway

Estrogen Signaling Pathway

Estrogen is a steroid hormone that is responsible for the regulation of growth, differentiation and function of the reproductive system. Estrogen signaling is often dysregulated in breast cancer and osteoporosis.