主页 / 药理学 / GPCRs / 7-TM Receptors / Adrenergic Receptors / Non-selective Adrenergic β Receptors / Non-selective Adrenergic β Receptor Antagonists / Bucindolol

Bucindolol

Cat. No. 2658 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2658 has been discontinued.

View all Non-selective Adrenergic β Receptors products.
说明： β1 and β2 antagonist
别名： MJ 13105
化学名： 2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile
纯度： ≥99% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for Bucindolol

Non-selective β-adrenoceptor antagonist with additional α1-adrenoceptor blocking activity. Ki values are 1.61, 1.20 and 68.9 nM for β1-, β2- and α1-adrenoceptors respectively. Also acts as a weak 5-HT2A/2B antagonist. Displays vasodilatory and antihypertensive actions.

技术数据 for Bucindolol

分子量 363.45
公式 C22H25N3O2
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 71119-11-4
Smiles CC(NCC(O)COC3=C(C#N)C=CC=C3)(C)CC1=CNC2=C1C=CC=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Bucindolol

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Bucindolol

参考文献是支持产品生物活性的出版物。

Watts et al (2000) Interaction of the [beta] adrenergic receptor antagonist bucindolol with serotonergic receptors. J.Cardiovasc.Pharmacol. 35 29 PMID: 10630730

Ponicke et al (2002) Differential effects of bucindolol and carve. on noradrenaline-induced hypertrophic response in ventricular cardiomyocytes of adult rats. J.Pharmacol.Exp.Ther. 301 71 PMID: 11907159

Marwood and Stokes (1985) Bucindolol has serotonin and alpha-adrenoceptor blocking properties. J.Cardiovasc.Pharmacol. 7 S67

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Non-selective Adrenergic β Receptor Antagonists

关键词: Bucindolol, Bucindolol supplier, α1-adrenoceptor, beta1-adrenoceptor, b1-adrenoceptor, b1-adrenergic, β1-Adrenergic, beta1-Adrenergic, α2-adrenoceptor, beta2-adrenoceptor, β2-adrenergic, α2-adrenergic, beta2-adrenergic, b2-adrenoceptor, antagonists, Receptors, Non-Selective, MJ, 13105, Non-selective, Adrenergic, Beta, 2658, Tocris Bioscience

篇 Bucindolol 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Bucindolol 的引用文献。

Bucindolol 的评论

目前没有该产品的评论。 Be the first to review Bucindolol and earn rewards!

Have you used Bucindolol?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.