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Submit ReviewBuprenorphine hydrochloride
说明： NOP agonist; also displays mixed action δ, κ and μ receptors
化学名： [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
纯度： ≥99% (HPLC)
生物活性 for Buprenorphine hydrochloride
Buprenorphine hydrochloride is a ORL1 receptor agonist that also displays mixed antagonist/partial agonist activity at κ, δ and μ-opioid receptors.
技术数据 for Buprenorphine hydrochloride
| 分子量 | 504.1 |
| 公式 | C29H41NO4.HCl |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 53152-21-9 |
| PubChem ID | 9848989 |
| InChI Key | UAIXRPCCYXNJMQ-HPRIMLMLSA-N |
| Smiles | OC1=CC=C3C2=C1O[C@@H]([C@@]7(OC)[C@]([C@@](C)(C(C)(C)C)O)([H])C4)[C@]52[C@@]4(CC7)[C@H](N(CC6CC6)CC5)C3.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Buprenorphine hydrochloride
参考文献 for Buprenorphine hydrochloride
参考文献是支持产品生物活性的出版物。
Wnendt et al (1999) Agonist effect of Bupren. in a nociceptin/OFQ receptor-triggered reporter gene assay. Mol.Pharmacol. 56 334 PMID: 10419552
Tzschentke (2002) Behavioral pharmacology of Bupren., with a focus on preclinical models of reward and addiction. Psychopharmacology 161 1 PMID: 11967625
关键词: Buprenorphine hydrochloride, Buprenorphine hydrochloride supplier, Opioids, receptors, ligands, Receptors, Miscellaneous/Non-selective, NOP, 2808, Tocris Bioscience
1 篇 Buprenorphine hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Buprenorphine hydrochloride 的部分引用包括：
Vidal et al (2016) Cell-Autonomous Regulation of Dendritic Spine Density by PirB. Eneuro 3 PMID: 27752542
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