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Submit ReviewBW 373U86
Discontinued Product
1663 has been discontinued.
说明： Potent, selective non-peptide δ agonist
化学名： 4-[(αR*)-α-((2S*,5R*)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide
纯度： ≥99% (HPLC)
生物活性 for BW 373U86
BW 373U86 is a potent, selective non-peptide δ-opioid receptor agonist. Ki values are 1.8, 15 and 34 nM for δ, μ and κ receptors respectively. Centrally active following systemic administration in vivo.
许可信息
Sold for research purposes under agreement from GlaxoSmithKline
技术数据 for BW 373U86
| 分子量 | 435.61 |
| 公式 | C27H37N3O2 |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 155836-50-3 |
| PubChem ID | 119029 |
| InChI Key | LBLDMHBSVIVJPM-YZIHRLCOSA-N |
| Smiles | O=C(N(CC)CC)C1=CC=C([C@@]([H])(N3C[C@@H](C)N(CC=C)C[C@@H]3C)C2=CC(O)=CC=C2)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BW 373U86
参考文献 for BW 373U86
参考文献是支持产品生物活性的出版物。
Broom et al (2002) Comparison of receptor mechanisms and efficacy requirements for δ-agonist-induced convulsive activity and antinociception in mice. J.Pharmacol.Exp.Ther. 303 723 PMID: 12388657
Chang et al (1993) A novel, potent and selective nonpeptidic delta opioid receptor agonist BW373U86. J.Pharmacol.Exp.Ther. 267 852 PMID: 8246159
Dykstra et al (1993) A novel delta opioid agonist, BW373U86, in squirrel monkeys responding under a schedule of shock titration. J.Pharmacol.Exp.Ther. 267 875 PMID: 8246162
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关键词: BW 373U86, BW 373U86 supplier, Potent, selective, non-peptide, δ-opioid, delta-opioid, agonists, DOP, Receptors, OP1, BW373U86, GlaxoSmithKline, GSK, Delta, Opioid, 1663, Tocris Bioscience
1 篇 BW 373U86 的引用文献
引用文献是使用了 Tocris 产品的出版物。 BW 373U86 的部分引用包括：
Donner et al (2013) Obesity improves myocardial ischaemic tolerance and RISK signalling in Ins-insensitive rats. J Allergy Clin Immunol 6 457 PMID: 23161371
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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