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Submit ReviewCarbazeran citrate is an aldehyde oxidase (AO) substrate. Exhibits activities as a phosphodiesterase inhibitor; produces concentration-dependent positive inotropic responses in isolated right atria.
Sold for research purposes under agreement from Pfizer Inc.
分子量 | 552.53 |
公式 | C18H24N4O4.C6H8O7 |
储存 | Store at +4°C |
纯度 | ≥98% (HPLC) |
CAS Number | 153473-94-0 |
PubChem ID | 90488940 |
InChI Key | QKMRPDVEKBYWPF-UHFFFAOYSA-N |
Smiles | O=C(NCC)OC(CC3)CCN3C2=NN=CC1=CC(OC)=C(OC)C=C12.OC(CC(C(O)=O)(O)CC(O)=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Hutzler et al (2011) Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes. Drug Metab.Dispos. 40 267 PMID: 22031625
Shahid and Rodger et al (1989) Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition. Br.J.Pharmacol. 98 291 PMID: 2478244
关键词: Carbazeran citrate, Carbazeran citrate supplier, Aldehyde, oxidases, AO, substrates, phosphodiesterase, inhibitors, inhibits, PDE, inotropic, Other, Oxygenases/Oxidases, Phosphodiesterases, 4420, Tocris Bioscience
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