Castanospermine

Name: Castanospermine
Brand: Tocris Bioscience
SKU: 0759

Cat. No. 0759 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0759 has been discontinued.

View all Glycosylases products.

说明： Glucosidases α and β inhibitor

化学名： [1S-(1α,6β,7α,8β,8aβ)]-Octahydro-1,6,7,8-indolizinetetrol

说明书

引用文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Castanospermine

Castanospermine is a potent inhibitor of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.

技术数据 for Castanospermine

分子量	189.21
公式	C₈H₁₅NO₄
储存	Store at RT
CAS Number	79831-76-8
PubChem ID	54445
InChI Key	JDVVGAQPNNXQDW-TVNFTVLESA-N
Smiles	[H][C@]12[C@@H](O)CCN1C[C@H](O)[C@@H](O)[C@@H]2O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Castanospermine

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Castanospermine

参考文献是支持产品生物活性的出版物。

Gruters et al (1987) Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature 330 74 PMID: 2959866

Saul et al (1984) Studies on the mechanism of castanospermine inhibition of α- and β-glucosidases. Arch.Biochem.Biophys. 230 668 PMID: 6424575

Welker et al (1987) Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine. Proc.Natl.Acad.Sci.U.S.A. 84 8120 PMID: 2825177

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Glycosylase Inhibitors

关键词: Castanospermine, Castanospermine supplier, β-glucosidases, beta-glucosidases, b-glucosidase, inhibitors, inhibits, a-Glucosidase, α-glucosidase, alpha-glucosidase, Glycosylases, Carbohydrate, Metabolism, 0759, Tocris Bioscience

1 篇 Castanospermine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Castanospermine 的部分引用包括：

Nacev et al (2011) The antifungal drug itracon. inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. J Biol Chem 286 44045 PMID: 22025615