Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewCCK Octapeptide, sulfated
说明： C-terminal octapeptide of CCK
别名： Cholecystokinin Octapeptide,sulfated,CCK-8
纯度： ≥95% (HPLC)
生物活性 for CCK Octapeptide, sulfated
CCK Octapeptide, sulfated is an endogenous C-terminal octapeptide of CCK found in the central nervous system and gastrointestinal tract.
Non-sulfated Peptide also available.
技术数据 for CCK Octapeptide, sulfated
| 分子量 | 1142.2 |
| 公式 | C49H62N10O16S3 |
| 序列 |
DYMGWMDF (Modifications: Tyr-2 = SO3H, Phe-8 = C-terminal amide) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 25126-32-3 |
| PubChem ID | 9833444 |
| InChI Key | IZTQOLKUZKXIRV-YRVFCXMDSA-N |
| Smiles | [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(OS(O)(=O)=O)C=C1)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for CCK Octapeptide, sulfated
| 溶解性 | Soluble to 0.50 mg/ml in PBS (pH 7.4) with sonication |
产品说明书 for CCK Octapeptide, sulfated
参考文献 for CCK Octapeptide, sulfated
参考文献是支持产品生物活性的出版物。
Beinfel (1997) CCK biosynthesis and processing: recent progress and future challenges. Life Sci. 61 2359 PMID: 9399627
Gaw et al (1995) Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat. Br.J.Pharmacol. 115 660 PMID: 7582487
Heinemann et al (1995) Mediation by CCKB receptors of the CCK-evoked hyperaemia in rat gastric mucosa. Br.J.Pharmacol. 116 2274 PMID: 8564259
Wank (1998) G-protein-coupled receptors in gastrointestinal physiology. I. CCK receptors: an exemplary family. Am.J.Physiol. 274 G607 PMID: 9575840
If you know of a relevant reference for CCK Octapeptide, sulfated, please let us know.
按产品操作查看相关产品
关键词: CCK Octapeptide, sulfated, CCK Octapeptide, sulfated supplier, C-terminal, octapeptide, CCK, Cholecystokinin, Non-Selective, Receptors, agonists, CCK-8, CCK8, Octapeptide,, sulfated, Non-selective, 1166, Tocris Bioscience
8 篇 CCK Octapeptide, sulfated 的引用文献
引用文献是使用了 Tocris 产品的出版物。 CCK Octapeptide, sulfated 的部分引用包括：
Caquineau et al (2010) Effects of cholecystokinin in the supraoptic nucleus and paraventricular nucleus are negatively modulated by leptin in 24-h fasted lean male rats. Autophagy 22 446 PMID: 20163516
D'Agostino et al (2016) Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit. Regul Pept 5 PMID: 26974347
Wu et al (2014) Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicol Sci 138 278 PMID: 24385417
Reidelberger et al (2014) Role of capsaicin-sensitive peripheral sensory neurons in anorexic responses to intravenous infusions of cholecystokinin, peptide YY-(3-36), and glucagon-like peptide-1 in rats. Am J Physiol Endocrinol Metab 307 E619 PMID: 25117406
Gamble et al (2013) Plasminogen activator inhibitor (PAI)-1 suppresses inhibition of gastric emptying by cholecystokinin (CCK) in mice. J Neuroendocrinol 185 41518 PMID: 23816469
Wang et al (2019) TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons. JCI Insight 4 PMID: 30843875
Hisadome et al (2011) CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs. Diabetes 60 2701 PMID: 21885869
Wang et al (2019) A bed nucleus of stria terminalis microcircuit regulating inflammation-associated modulation of feeding. Nat Commun 10 2769 PMID: 31235690
您是否知道使用了 Tocris CCK Octapeptide, sulfated 的优秀论文？ 请告知我们.
CCK Octapeptide, sulfated 的评论
平均评分: 4 (Based on 1 Review.)
Have you used CCK Octapeptide, sulfated?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by:
Applied to colon tissue.
By
John Broad on 01/05/2018
分析类型： In Vitro
种属： Human
1uM CCK contracts GI smooth muscle
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.