Chlormethiazole hydrochloride

Discontinued Product

0881 has been discontinued.

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说明: Potentiates GABAA receptor function
化学名: 5-(2-Chloroethyl)-4-methylthiazole hydrochloride
纯度: ≥99% (HPLC)
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引用文献
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生物活性 for Chlormethiazole hydrochloride

Chlormethiazole hydrochloride is a sedative and anticonvulsant which is neuroprotective in a number of animal models. Prevents the degeneration of serotonergic nerve terminals induced by MDMA ('Ecstasy').

技术数据 for Chlormethiazole hydrochloride

分子量 198.11
公式 C6H8ClNS.HCl
储存 Desiccate at RT
纯度 ≥99% (HPLC)
CAS Number 6001-74-7
PubChem ID 19035073
InChI Key OFXYKSLKNMTBHK-UHFFFAOYSA-N
Smiles ClCCC1=C(C)N=CS1.Cl

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参考文献 for Chlormethiazole hydrochloride

参考文献是支持产品生物活性的出版物。

Cross et al (1995) The protective action of chloromethiazole against ischaemia induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity. Br.J.Pharmacol. 114 1625 PMID: 7599932

Hewitt and Green (1994) Chloromethiazole, dizocilpine and halope. prevent the degeneration of serotonergic nerve terminals induced by the administration of MDMA ('Ecstasy') to rats. Neuropharmacology 33 1589 PMID: 7539115

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关键词: Chlormethiazole hydrochloride, Chlormethiazole hydrochloride supplier, Potentiates, GABAA, receptor, function, Receptors, modulators, 0881, Tocris Bioscience

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