Chlorpromazine hydrochloride

Name: Chlorpromazine hydrochloride
Brand: Tocris Bioscience
SKU: 4097

Cat. No. 4097 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4097 has been discontinued.

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说明： Antipsychotic; D₂ and H₁ antagonist

别名： CPZ

化学名： 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Chlorpromazine hydrochloride

Dopamine receptor antagonist; reduces neurotransmitter binding. Inhibits nitric oxide synthesis in mouse brain cytosol. Also an antagonist of nAChR, histamine and 5-HT receptors. Displays growth-inhibitory effects on numerous tumor cell lines. Exhibits antipsychotic activity.

技术数据 for Chlorpromazine hydrochloride

分子量	355.33
公式	C₁₇H₁₉ClN₂S.HCl
储存	Desiccate at RT
纯度	≥99% (HPLC)
CAS Number	69-09-0
Smiles	ClC3=CC2=C(C=C3)SC1=CC=CC=C1N2CCCN(C)C.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Chlorpromazine hydrochloride

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化学品安全技术说明书

参考文献 for Chlorpromazine hydrochloride

参考文献是支持产品生物活性的出版物。

Martinez and Coleman (1990) A comparison of the effects of chlorprom. and more selective histamine and 5-hydroxytryptamine antagonists on human IgG synthesis in vitro. Int.J.Immunopharmacol. 12 185 PMID: 2329012

Eisenberg et al (2008) Differential interference of chlorprom. with the membrane interactions of oncogenic K-ras and its effects on cell growth. J.Biol.Chem. 283 27279 PMID: 18693247

Chiara et al (2009) [³H]chlorpromazine photolabeling of the Torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel. Biochemistry 48 10066 PMID: 19754159

Palacios et al (1993) Chlorpromazine inhibits both the constitutive nitric oxide synthase and the induction of nitric oxide synthase after LPS challenge. Biochem.Biophys.Res.Comms. 196 280

Cohen et al (1997) Characterization of the discriminative stimulus produced by the DA antagonist tiapride. J.Pharm.Exp.Ther. 283 573

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Miscellaneous Compounds

关键词: Chlorpromazine hydrochloride, Chlorpromazine hydrochloride supplier, Chlorpromazine, HCl, dopamine, D2, receptor, antagonist, histamine, H1, antagonists, CPZ, Miscellaneous, Compounds, 4097, Tocris Bioscience

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