CMPDA

Discontinued Product

4373 has been discontinued.

View all AMPA Receptors products.
说明: Positive allosteric modulator of GluA2 receptors
化学名: N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide
纯度: ≥98% (HPLC)
说明书
引用文献
评论
文献 (4)

生物活性 for CMPDA

CMPDA is a positive allosteric modulator of GluA2 receptors (EC50 values are 45.4 and 63.4 nM at GluA2i and GluA2o respectively, in a calcium influx screening assay). Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.

技术数据 for CMPDA

分子量 376.53
公式 C16H28N2O4S2
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 380607-77-2
PubChem ID 9969799
InChI Key FHLGMMYEKXPVSC-UHFFFAOYSA-N
Smiles O=S(NCCC1=CC=C(CCNS(=O)(C(C)C)=O)C=C1)(C(C)C)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for CMPDA

参考文献是支持产品生物活性的出版物。

Timm et al (2011) Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol. 80 267 PMID: 21543522

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关键词: CMPDA, CMPDA supplier, Positive, allosteric, modulators, GluR2, GluA2, AMPA, receptors, GluR2i, GluA2i, GluR2o, GluA2o, PAM, Receptors, 4373, Tocris Bioscience

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