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Submit ReviewCoenzyme Q10
说明： Antioxidant
化学名： 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
纯度： ≥99% (HPLC)
生物活性 for Coenzyme Q10
Coenzyme Q10 is a component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Coenzyme Q10 displays neuroprotective activity. In an animal model of Huntington's disease, Coenzyme Q10 extends survival and delays disease; this effect is more pronounced when combined with Remacemide hydrochloride (Cat. No. 1622). Ferroptosis inhibitor.
技术数据 for Coenzyme Q10
| 分子量 | 863.34 |
| 公式 | C59H90O4 |
| 储存 | Store at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 303-98-0 |
| PubChem ID | 5281915 |
| InChI Key | ACTIUHUUMQJHFO-UPTCCGCDSA-N |
| Smiles | O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=C(C)C1=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Coenzyme Q10
参考文献 for Coenzyme Q10
参考文献是支持产品生物活性的出版物。
Shults (2003) Coenzyme Q10 in neurodegenerative diseases. Curr.Med.Chem. 10 1917 PMID: 12871093
Young et al (2007) Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 12 62 PMID: 17192765
Yang and Stockwell et al (2016) Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 26 165 PMID: 26653790
Ferrante et al (2002) Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J.Neurosci. 22 1592 PMID: 11880489
关键词: Coenzyme Q10, Coenzyme Q10 supplier, Antioxidant, CoenzymeQ10, Antioxidants, Ferroptosis, 3003, Tocris Bioscience
1 篇 Coenzyme Q10 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Coenzyme Q10 的部分引用包括：
Martin et al (2014) Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol 7 101 PMID: 23653115
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