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Submit ReviewCompstatin control peptide is a control peptide for Compstatin, a complement inhibitor.
Active Analog also available.
分子量 | 1488.67 |
公式 | C66H101N23O17 |
序列 |
IAVVQDWGHHRAT (Modifications: Thr-13 = C-terminal amide) |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 301544-78-5 |
PubChem ID | 90488879 |
InChI Key | SAJZITDYWAOPDD-LSPMIEDISA-N |
Smiles | [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性 | Soluble to 1 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Sahu et al (1996) Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. J.Immunol. 157 884 PMID: 8752942
Fiane et al (1999) Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts. Xenotransplantation 6 52 PMID: 10355733
Mollnes et al (2002) Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100 1869 PMID: 12176911
If you know of a relevant reference for Compstatin control peptide, please let us know.
关键词: Compstatin control peptide, Compstatin control peptide supplier, C3-binding, protein, inhibits, inhibitors, complement, activation, Convertase, control, peptide, Complement, 3796, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Compstatin control peptide 的部分引用包括:
Yumi et al (2023) Complement dependent TNFα production in neutrophil-like HL60 cells. Biochem Biophys Rep 34 101465 PMID: 37125077
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