Cyclofenil

Name: Cyclofenil
Brand: Tocris Bioscience
SKU: 3999

Cat. No. 3999 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3999 has been discontinued.

View all Estrogen and Related Receptors products.

说明： Selective estrogen receptor modulator (SERM)

化学名： 4,4'-(Cyclohexylidenemethylene)bisphenol 1,1'-diacetate

纯度： ≥99% (HPLC)

说明书

引用文献

通路 (1)

生物活性技术数据说明书参考文献

生物活性 for Cyclofenil

Non-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor β (ERβ) than for ERα.

技术数据 for Cyclofenil

分子量	364.43
公式	C₂₃H₂₄O₄
储存	Store at +4°C
纯度	≥99% (HPLC)
CAS Number	2624-43-3
PubChem ID	2898
InChI Key	GVOUFPWUYJWQSK-UHFFFAOYSA-N
Smiles	CC(OC(C=C3)=CC=C3/C(C2=CC=C(OC(C)=O)C=C2)=C1/CCCCC1)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Cyclofenil

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Cyclofenil

参考文献是支持产品生物活性的出版物。

Kieser et al (2010) Characterization of the pharmacore properties of novel selective estrogen receptor downregulators (SERDs). J.Med.Chem. 53 3320 PMID: 20334372

Seo et al (2006) Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential PET agents for imaging estrogen receptors in breast cancer. J.Med.Chem. 49 2496 PMID: 16610793

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Estrogen and Related Receptors

关键词: Cyclofenil, Cyclofenil supplier, Non-steroidal, selective, estrogen, receptors, modulators, SERM, ERα, ERβ, Estrogen, and, Related, Receptors, 3999, Tocris Bioscience

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Pathways for Cyclofenil

Estrogen Signaling Pathway

Estrogen is a steroid hormone that is responsible for the regulation of growth, differentiation and function of the reproductive system. Estrogen signaling is often dysregulated in breast cancer and osteoporosis.