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Submit Review[D-Ala2]-Deltorphin II
说明： Selective δ agonist peptide
纯度： ≥95% (HPLC)
生物活性 for [D-Ala2]-Deltorphin II
[D-Ala2]-Deltorphin II is a selective peptide agonist for the δ opioid receptor. Antinociceptive in vivo.
技术数据 for [D-Ala2]-Deltorphin II
| 分子量 | 782.89 |
| 公式 | C38H54N8O10 |
| 序列 |
YAFEVVG (Modifications: Ala-2 = D-Ala, Gly-7 = C-terminal amide) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 122752-16-3 |
| PubChem ID | 10033203 |
| InChI Key | NUNBRHVOPFWRRG-RCEFDBTISA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for [D-Ala2]-Deltorphin II
| 溶解性 | Soluble to 1 mg/ml in water |
产品说明书 for [D-Ala2]-Deltorphin II
参考文献 for [D-Ala2]-Deltorphin II
参考文献是支持产品生物活性的出版物。
Mattia et al (1991) Lack of antinociceptive cross-tolerance between [D-Pen2, D-Pen5]enkephalin and [D-Ala2]deltorphin II in mice: evidence for delta receptor subtypes. J.Pharmacol.Exp.Ther. 258 583 PMID: 1650835
Sanchez-Blazquez (1998) Delta opioid receptor subtypes activate inositol-signalling pathways in the production of antinociception. J.Pharmacol.Exp.Ther. 285 820 PMID: 9580632
Thomas et al (1997) Structure-activity relationships of a series of [D-Ala2] deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. J.Pharmacol.Exp.Ther. 281 817 PMID: 9152390
If you know of a relevant reference for [D-Ala2]-Deltorphin II, please let us know.
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关键词: [D-Ala2]-Deltorphin II, [D-Ala2]-Deltorphin II supplier, Selective, δ-opioid, delta-opioid, agonist, peptide, DOP, Receptors, OP1, [D-Ala2]-DeltorphinII, Delta, Opioid, 1180, Tocris Bioscience
4 篇 [D-Ala2]-Deltorphin II 的引用文献
引用文献是使用了 Tocris 产品的出版物。 [D-Ala2]-Deltorphin II 的部分引用包括：
Krook-Magnuson et al (2011) Ivy and neurogliaform interneurons are a major target of μ-opioid receptor modulation. J Neurosci 31 14861 PMID: 22016519
Kharmate et al (2013) Inhibition of tumor promoting signals by activation of SSTR2 and opioid receptors in human breast cancer cells. Cancer Cell Int 13 93 PMID: 24059654
Schuster et al (2015) Ligand requirements for involvement of PKCη in synergistic analgesic interactions between spinal μ and δ opioid receptors. Arthritis Res Ther 172 642 PMID: 24827408
Laurent et al (2014) δ-opioid and DArgic processes in accumbens shell modulate the cholinergic control of predictive learning and choice. J Neurosci 34 1358 PMID: 24453326
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