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Submit ReviewD-Aspartic acid is an endogenous NMDA receptor agonist with similar activity to the L-isomer. Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.
L-isomer also available.
分子量 | 133.1 |
公式 | C4H7NO4 |
储存 | Store at RT |
CAS Number | 1783-96-6 |
PubChem ID | 83887 |
InChI Key | CKLJMWTZIZZHCS-UWTATZPHSA-N |
Smiles | N[C@@]([H])([C@](O)=O)CC(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Hashimoto et al (1997) Free D-aspartate and D-serine in the mammalian brain and periphery. Prog.Neurobiol. 53 325 PMID: 9247969
Ishio et al (1998) D-Aspartate modulates melatonin synthesis in rat pinealocytes. Neurosci.Lett. 249 143 PMID: 9682837
Olverman et al (1988) Structure/activity relations of NMDA receptor ligands as studied by their inhibition of 3H-D-AP5 binding in rat brain membranes. Neuroscience 26 17 PMID: 2901691
关键词: D-Aspartic acid, D-Aspartic acid supplier, NMDA, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Amino, Acids, 0213, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 D-Aspartic acid 的部分引用包括:
Cai and Ford (2018) DA Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of DA and Glutamate. Cell Rep 25 3148 PMID: 30540946
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
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