[D-Trp^7,9,10]-Substance P

Name: [D-Trp 7,9,10 ]-Substance P
Brand: Tocris Bioscience
SKU: 1884

Cat. No. 1884 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1884 has been discontinued.

View all Heterotrimeric G-protein GTPases products.

说明： Inhibits M₁ ACh receptor activation of G_q/11

别名： GPAnt-2 analog

说明书

引用文献 (1)

生物活性技术数据说明书参考文献

生物活性 for [D-Trp^7,9,10]-Substance P

[D-Trp^7,9,10]-Substance P is a substance P analog that inhibits activation of G_q/11 by M₁ muscarinic ACh receptors. Does not inhibit G_i/o activation by M₂ ACh receptors.

技术数据 for [D-Trp^7,9,10]-Substance P

分子量	1588.89
公式	C₇₉H₁₀₅N₂₁O₁₃S
序列	RPKPQQWFWWM (Modifications: Trp-7, Trp-9, Trp-10 = D-Trp, Met-11 = C-terminal Amide)
储存	Store at -20°C
CAS Number	89430-38-6
PubChem ID	16143852
InChI Key	ZDXXOQXJCDHSRG-GGDSLUOHSA-N
Smiles	[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for [D-Trp^7,9,10]-Substance P

分析证书/产品说明书

化学品安全技术说明书

参考文献 for [D-Trp^7,9,10]-Substance P

参考文献是支持产品生物活性的出版物。

Mukai et al (1992) G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J.Biol.Chem. 267 16237 PMID: 1379592

按标靶查看相关产品

关键词: [D-Trp 7,9,10]-Substance P, [D-Trp 7,9,10]-Substance P supplier, inhibitors, inhibits, M1, ACh, receptor, activation, Gq/11, G-Protein, Heterotrimeric, [D-Trp7910]-SubstanceP, GPAnt-2, analog, G-protein, GTPases, 1884, Tocris Bioscience

1 篇 [D-Trp^7,9,10]-Substance P 的引用文献

引用文献是使用了 Tocris 产品的出版物。 [D-Trp^7,9,10]-Substance P 的部分引用包括：

Nordman and Kabbani (2014) Microtubule dynamics at the growth cone are mediated by α7 nicotinic receptor activation of a Gαq and IP3 receptor pathway. Diabetes 28 2995 PMID: 24687992