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Daidzein

Cat. No. 1417 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1417 has been discontinued.

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说明： Arrests cell cycle in G1 phase
化学名： 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
纯度： ≥99% (HPLC)
说明书
引用文献
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文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for Daidzein

Daidzein is an analog of the phytoestrogen genistein (Cat. No. 1110). Blocks G1 phase cell cycle progression. Agonist at estrogen receptors.

技术数据 for Daidzein

分子量 254.24
公式 C15H10O4
储存 Desiccate at -20°C
纯度 ≥99% (HPLC)
CAS Number 486-66-8
PubChem ID 5281708
InChI Key ZQSIJRDFPHDXIC-UHFFFAOYSA-N
Smiles OC1=CC=C(C=C1)C1=COC2=CC(O)=CC=C2C1=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Daidzein

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Daidzein

参考文献是支持产品生物活性的出版物。

Casanova et al (1999) Development effects of dietary phytoestrogens in Sprague Dawley rats and interactions of genistein and daidzein with rat estrogen receptors α and β in vitro. Toxicol.Sci. 51 236 PMID: 10543025

Higashi and Ogawara (1994) Daidzein inhibits Ins- or Ins-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. Biochim.Biophys.Acta 1221 29 PMID: 8130274

Jing et al (1993) Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo. Anticancer Res. 13 1049 PMID: 8352524

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该领域的文献

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Cell Cycle and DNA Damage Research Product Guide

Cell Cycle and DNA Damage Research Product Guide

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Cell Cycle & DNA Damage Repair Poster

In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. This poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.