Desipramine hydrochloride

Cat. No. 3067 8 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Selective inhibitor of noradrenalin transporters

化学名： 10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride

纯度： ≥99% (HPLC)

引用文献 (8)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Desipramine hydrochloride

Desipramine hydrochloride is a tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (K_i values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).

技术数据 for Desipramine hydrochloride

分子量	302.84
公式	C₁₈H₂₂N₂.HCl
储存	Desiccate at +4°C
纯度	≥99% (HPLC)
CAS Number	58-28-6
PubChem ID	65327
InChI Key	XAEWZDYWZHIUCT-UHFFFAOYSA-N
Smiles	CNCCCN2C1=CC=CC=C1CCC3=C2C=CC=C3.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Desipramine hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	30.28	100

制备储备液 for Desipramine hydrochloride

以下数据基于产品分子量 302.84。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.3 mL	16.51 mL	33.02 mL
5 mM	0.66 mL	3.3 mL	6.6 mL
10 mM	0.33 mL	1.65 mL	3.3 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

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产品说明书 for Desipramine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Desipramine hydrochloride

参考文献是支持产品生物活性的出版物。

Torres et al (2003) Plasma membrane monoamine transporters: structure, regulation and function. Nat.Rev.Neurosci. 4 13 PMID: 12511858

Zhao et al (2008) NE transporter regulation mediates the long-term behavioral effects of the antidepressant desipr. Neuropsychopharmacol. 33 3190

If you know of a relevant reference for Desipramine hydrochloride, please let us know.

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