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Submit ReviewNitric oxide donor. Activates an inward current in cultured rat cerebellar granules cells. Increases cGMP production in cultured vascular smooth muscle cells. Reduces contractility of cardiac muscle preparations in vitro.
分子量 | 163.18 |
公式 | C4H13N5O2 |
储存 | Store at -20°C |
CAS Number | 146724-94-9 |
PubChem ID | 1606 |
InChI Key | HMRRJTFDJAVRMR-UHFFFAOYSA-N |
Smiles | NCCN(N(N=O)O)CCN |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Thompson et al (2009) The NO donor DETA-NONOate reversibly activates an inward current in neurones and is not mediated by the released nitric oxide. Br.J.Pharmacol. 158 1338 PMID: 19785659
Olson et al (1997) Selective guanylyl cyclase inhibitor reverses nitric oxide-induced vasorelaxation. Hypertension 29 254 PMID: 9039111
Wegener et al (2002) Effects of nitric oxide donors on cardiac contractility in wild-type and myoglobin-deficient mice. Br.J.Pharmacol. 136 415 PMID: 12023944
关键词: DETA NONOate, DETA NONOate supplier, nitric, oxide, releasing, compounds, donors, NO, Donors, /, Precursors, ROS, 6077, Tocris Bioscience
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