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Submit ReviewDilazep dihydrochloride is a coronary and cerebral vasodilator, suppresses the effects of ischemia. Inhibitor of platelet aggregation and of membrane transport of nucleosides. Inhibits adenosine uptake.
分子量 | 677.62 |
公式 | C31H44N2O10.2HCl |
储存 | Store at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 20153-98-4 |
PubChem ID | 29976 |
InChI Key | VILIWRRWAWKXRW-UHFFFAOYSA-N |
Smiles | Cl.Cl.COC1=CC(=CC(OC)=C1OC)C(=O)OCCCN1CCCN(CCCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CC1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 100 |
以下数据基于产品分子量 677.62。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.48 mL | 7.38 mL | 14.76 mL |
5 mM | 0.3 mL | 1.48 mL | 2.95 mL |
10 mM | 0.15 mL | 0.74 mL | 1.48 mL |
50 mM | 0.03 mL | 0.15 mL | 0.3 mL |
参考文献是支持产品生物活性的出版物。
Kawagoe et al (1992) Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study. Naunyn Schmiedebergs Arch.Pharmacol. 345 485 PMID: 1620248
Zhang et al (1991) Dilazep potentation of adenosine-mediated superior mesenteric arterial vasodilation. J.Pharmacol.Exp.Ther. 258 767 PMID: 1890619
If you know of a relevant reference for Dilazep dihydrochloride, please let us know.
关键词: Dilazep dihydrochloride, Dilazep dihydrochloride supplier, adenosines, reuptake, inhibitors, inhibits, ENT1, Purine, Transporters, Pyrimidine, Equilibrative, Nucleoside, Monoamine, Neurotransmitter, vasodilator, 0481, Tocris Bioscience
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